Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10400093 | 0.90 | SRC (0.47) | PNMTALDH1A1MAPTCYP3A4ALOX15 | |
| 2-Chloropyridine SCHEMBL9390160 | 0.85 | TDP1 (0.41) | PNMTALDH1A1MAPTTDP1HTR2A | |
| Quinoline SCHEMBL27724871 | 0.84 | POLB (0.49) | ALDH1A1MAPTTDP1TSHRPDE10A | |
| Ethoxycarbonyl Group SCHEMBL27597891 | 0.84 | PNMT (0.36) | PNMTALDH1A1MAPTCYP3A4ALOX15 | |
| SCHEMBL28083310 | 0.83 | PNMT (0.36) | PNMTALDH1A1MAPTCYP3A4ALOX15 | |
| SCHEMBL4718488 | 0.78 | ACHE (0.50) | PNMTALDH1A1MAPTCYP3A4ALOX15 | |
| SCHEMBL6200472 | 0.78 | MAPT (0.57) | PNMTALDH1A1MAPTALOX15HSD17B10 | |
| Indoline SCHEMBL27976781 | 0.77 | ALDH1A1 (0.51) | PNMTALDH1A1MAPTCYP3A4ALOX15 | |
| SCHEMBL9501421 | 0.76 | TDP1 (0.45) | PNMTALDH1A1MAPTHSD17B10TDP1 | |
| SCHEMBL31357065 | 0.76 | TDP1 (0.45) | PNMTALDH1A1MAPTHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12427196-B2 | Macromolecular prodrugs for light-emitting diodes and uses thereof | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-09-30 | — | — | US | claimed |
| US-12227613-B2 | Photo-patternable organic semiconductor (OSC) polymers and methods of formation and applications thereof | CORNING INCORPORATED (US) | 2025-02-18 | — | — | US | claimed |
| WO-2025029623-A2 | LIGHT-TRIGGERED POLYMER-NALOXONE CONJUGATE FOR OPIOID REVERSAL | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-02-06 | — | — | WO | claimed |
| US-20230346942-A1 | MACROMOLECULAR PRODRUGS FOR LIGHT-EMITTING DIODES AND USES THEREOF | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-11-02 | — | — | US | claimed |
| US-20220411790-A1 | A CRISPR-CAS9 PLATFORM WITH AN INTRINSIC OFF-SWITCH AND ENHANCED SPECIFICITY | THE JOHNS HOPKINS UNIVERSITY | 2022-12-29 | — | — | US | claimed |
| EP-4090374-A1 | MACROMOLECULAR PRODRUGS FOR LIGHT-EMITTING DIODES AND USES THEREOF | Children's Medical Center Corporation (US) | 2022-11-23 | — | — | EP | claimed |
| CN-114380982-A | Photopatternable Organic Semiconductor (OSC) polymers, methods of forming the same, and uses thereof | 康宁股份有限公司 | 2022-04-22 | — | — | CN | claimed |
| US-20220119591-A1 | PHOTO-PATTERNABLE ORGANIC SEMICONDUCTOR (OSC) POLYMERS AND METHODS OF FORMATION AND APPLICATIONS THEREOF | CORNING INCORPORATED | 2022-04-21 | — | — | US | claimed |
| WO-2021146553-A1 | MACROMOLECULAR PRODRUGS FOR LIGHT-EMITTING DIODES AND USES THEREOF | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2021-07-22 | — | — | WO | claimed |
| WO-2021081468-A1 | A CRISPR-CAS9 PLATFORM WITH AN INTRINSIC OFF-SWITCH AND ENHANCED SPECIFICITY | THE JOHNS HOKINS UNIVERSITY (US) | 2021-04-29 | — | — | WO | claimed |
| CN-104399364-A | Method of utilizing nitryl-containing ionic liquid to absorb sulfur dioxide gas | UNIV HENAN NORMAL | 2015-03-11 | — | — | CN | claimed |
| WO-2014150851-A1 | NUCLEOTIDE ANALOGS FOR SEQUENCING | IBIS BIOSCIENCES, INC. (US) | 2014-09-25 | — | — | WO | claimed |
| CN-103880730-A | Chemical synthesis method of 7-nitroindole-3-tert butyl formate | UNIV NANTONG | 2014-06-25 | — | — | CN | claimed |
| EP-1757585-B1 | Anionically substituted 7-Nitroindoline derivatives and their uses | MEDICAL RES COUNCIL (GB) | 2010-12-01 | — | — | EP | claimed |
| EP-1377548-B1 | PROCESS FOR NITRATING PHOTOCLEAVABLE COMPOUNDS | MEDICAL RES COUNCIL (GB) | 2009-02-18 | — | — | EP | claimed |
| US-20070203099-A1 | Anionically substituted 7-nitroindoline derivatives and their uses | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2007-08-30 | — | — | US | claimed |
| EP-1757585-A1 | Anionically substituted 7-Nitroindoline derivatives and their uses | Medical Research Council (GB) | 2007-02-28 | — | — | EP | claimed |
| US-20040171846-A1 | Process for nitrating photocleavable compounds | MEDICAL RESEARCH COUNCIL (GB) | 2004-09-02 | — | — | US | claimed |
| EP-1377548-A1 | PROCESS FOR NITRATING PHOTOCLEAVABLE COMPOUNDS | MEDICAL RESEARCH COUNCIL (GB) | 2004-01-07 | — | — | EP | claimed |
| WO-2002083639-A1 | PROCESS FOR NITRATING PHOTOCLEAVABLE COMPOUNDS | MEDICAL RESEARCH COUNCIL (GB) | 2002-10-24 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171846-A1 | Process for nitrating photocleavable compounds | NOS2, SOD1, NIT2 | PNMT 1184/4885ALDH1A1 175/4885MAPT 3106/4885 |
| US-20070203099-A1 | Anionically substituted 7-nitroindoline derivatives and their uses | SLC18A3, SLC18A1, SLC18A2 | PNMT 34/4885ALDH1A1 2026/4885MAPT 2542/4885 |
| US-12427196-B2 | Macromolecular prodrugs for light-emitting diodes and uses thereof | CRY1, MAPT, PYGL | PNMT 4558/4885ALDH1A1 650/4885MAPT 2/4885 |
| US-20230346942-A1 | MACROMOLECULAR PRODRUGS FOR LIGHT-EMITTING DIODES AND USES THEREOF | CRY1, MAPT, PYGL | PNMT 4558/4885ALDH1A1 650/4885MAPT 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.