Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 12/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 11/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583665 | 0.86 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP19A1CYP17A1CYP1A2 | |
| SCHEMBL27705309 | 0.80 | PRCP (0.41) | — | |
| SCHEMBL14112685 | 0.72 | PRKAB2 (0.46) | CYP11B1CYP11B2CYP19A1CYP17A1CYP1A2 | |
| SCHEMBL14112652 | 0.72 | PRKAB2 (0.46) | CYP11B1CYP11B2CYP19A1CYP17A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL4621277 | 0.71 | PRKAB2 (0.45) | CYP11B1CYP11B2CYP19A1CYP17A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL4621550 | 0.71 | PRKAB2 (0.45) | CYP11B1CYP11B2CYP19A1CYP17A1CYP1A2 | |
| SCHEMBL27705416 | 0.71 | HTR1A (0.50) | CYP1A2ALDH1A1CYP2A6CYP3A4TDO2 | |
| SCHEMBL4595328 | 0.71 | CYP11B1 (0.43) | CYP11B1CYP11B2CYP19A1CYP17A1CYP1A2 | |
| SCHEMBL4595329 | 0.71 | MAOA (0.47) | CYP11B1CYP11B2CYP19A1CYP17A1CYP1A2 | |
| SCHEMBL23640835 | 0.70 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1CYP17A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101203505-A | Chromane and chromene derivatives and uses thereof | WYETH CORP (US) | 2008-06-18 | — | — | CN | disclosed |