Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 6/20 | 0.40 |
| ▸ | HTR1A | P08908 | 5/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | IL1RN | P18510 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27725876 | 0.80 | CYP11B1 (0.49) | — | |
| SCHEMBL27725850 | 0.79 | HTR7 (0.42) | HTR7HTR1A | |
| SCHEMBL27705416 | 0.78 | HTR1A (0.50) | HTR7HTR1A | |
| SCHEMBL28230835 | 0.76 | PARP1 (0.47) | PRCPHTR7HTR1ADRD2ANPEP | |
| SCHEMBL27725874 | 0.75 | PNMT (0.45) | — | |
| SCHEMBL27980979 | 0.73 | HTR7 (0.43) | PRCPHTR7HTR1ADRD2 | |
| SCHEMBL4362031 | 0.70 | HTR7 (0.41) | PRCPHTR7HTR1ADRD2 | |
| SCHEMBL28415 | 0.67 | MAOA (0.41) | — | |
| SCHEMBL14112791 | 0.66 | HTR7 (0.43) | HTR7HTR1ADRD2ANPEPIL1RN | |
| SCHEMBL4958298 | 0.66 | NPC1 (0.33) | HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101203505-A | Chromane and chromene derivatives and uses thereof | WYETH CORP (US) | 2008-06-18 | — | — | CN | disclosed |