Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 4/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27688421 | 0.81 | ALAD (0.34) | LMNAMAPTGAAALDH1A1KMT2A | |
| SCHEMBL27823662 | 0.81 | PTGS1 (0.38) | LMNAMAPTGAAALDH1A1KMT2A | |
| SCHEMBL27728734 | 0.81 | ALDH1A1 (0.36) | TP53MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL1483093 | 0.78 | LMNA (0.37) | TP53TSHRLMNATYRKIF11 | |
| SCHEMBL27746910 | 0.77 | EGFR (0.35) | TP53TSHRMAPTEP300KDM4E | |
| SCHEMBL27726013 | 0.77 | LMNA (0.36) | TP53TSHRLMNATYRKIF11 | |
| SCHEMBL5739422 | 0.75 | ESRRG (0.43) | LMNAMAPTGAAKMT2AGRIN2C | |
| SCHEMBL27707783 | 0.75 | ERN1 (0.34) | — | |
| SCHEMBL27688422 | 0.74 | AHR (0.36) | LMNAMAPTKDM4EGAAALDH1A1 | |
| SCHEMBL5738665 | 0.73 | CA1 (0.43) | LMNAMAPTKDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103360290-B | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL IND LTD | 2015-04-01 | — | — | CN | disclosed |
| CN-103435593-B | Process for production of thiophene compound and intermediate thereof | NISSAN CHEMICAL IND LTD | 2015-01-28 | — | — | CN | disclosed |
| CN-103435593-A | Process for production of thiophene compound and intermediate thereof | NISSAN CHEMICAL IND LTD | 2013-12-11 | — | — | CN | disclosed |
| CN-103360290-A | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL IND LTD | 2013-10-23 | — | — | CN | disclosed |
| CN-101959875-B | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL IND LTD | 2013-10-16 | — | — | CN | disclosed |
| CN-101072766-B | 3-ethylidenehydrazino substituted heterocyclic compounds as thrombopoietin receptor activators | NISSAN CHEMICAL IND LTD | 2012-05-02 | — | — | CN | disclosed |
| CN-101386596-B | 3-alkylidenehydrazino substituted heteroaryl compounds as thrombopoietin receptor activators | NISSAN CHEMICAL IND LTD | 2011-10-26 | — | — | CN | disclosed |
| CN-101076519-B | Amide compound and thrombopoietin receptor activator | NISSAN CHEMICAL IND LTD | 2011-07-20 | — | — | CN | disclosed |
| CN-101959875-A | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL IND LTD | 2011-01-26 | — | — | CN | disclosed |
| CN-101386596-A | 3-alkylidenehydrazino substituted heteroaryl compounds as thrombopoietin receptor activators | NISSAN CHEMICAL IND LTD (JP) | 2009-03-18 | — | — | CN | disclosed |
| CN-100443472-C | 3-alkylidenehydrazino substituted heteroaryl compound and medicine containing the same | NISSAN CHEMICAL IND LTD (JP) | 2008-12-17 | — | — | CN | disclosed |