Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869947 | 0.86 | ALDH1A1 (0.49) | ALDH1A1HSD17B10MAPTCYP1A2CYP2C9 | |
| SCHEMBL30796294 | 0.81 | SMN1; SMN2 (0.50) | ALDH1A1HSD17B10MAPTCYP1A2CYP2C9 | |
| SCHEMBL8854931 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HSD17B10MAPTCYP1A2CYP2C9 | |
| SCHEMBL13499619 | 0.81 | L3MBTL1 (0.46) | ALDH1A1HSD17B10MAPTHPGDMEN1 | |
| SCHEMBL27678665 | 0.80 | ALDH1A1 (0.49) | ALDH1A1HSD17B10MAPTCYP1A2CYP2C9 | |
| SCHEMBL1363531 | 0.79 | L3MBTL1 (0.55) | ALDH1A1HSD17B10MAPTCYP1A2CYP2C9 | |
| SCHEMBL442790 | 0.78 | CHRNB2 (0.59) | ALDH1A1HSD17B10MAPTCYP1A2CYP2C9 | |
| Benzene SCHEMBL1720409 | 0.78 | CHRNB2 (0.59) | ALDH1A1HSD17B10MAPTCYP1A2CYP2C9 | |
| SCHEMBL874326 | 0.78 | CTDSP1 (0.73) | ALDH1A1HSD17B10MAPTCYP1A2CYP2C9 | |
| SCHEMBL31147823 | 0.78 | L3MBTL1 (0.53) | ALDH1A1HSD17B10MAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101356173-A | Novel pyridopyrazines and their use as modulators of kinases | AETERNA ZENTARIS GMBH (DE) | 2009-01-28 | — | — | CN | claimed |
| CN-101356173-B | Novel pyridopyrazines and their use as modulators of kinases | AETERNA ZENTARIS GMBH | 2012-10-31 | — | — | CN | disclosed |
| CN-101356173-A | Novel pyridopyrazines and their use as modulators of kinases | AETERNA ZENTARIS GMBH (DE) | 2009-01-28 | — | — | CN | disclosed |