Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089461 | 0.84 | KDM4E (0.46) | KDM4EL3MBTL1ALDH1A1TAAR1OPRM1 | |
| SCHEMBL5754344 | 0.84 | TAAR1 (0.47) | KDM4EL3MBTL1ALDH1A1TAAR1OPRM1 | |
| SCHEMBL8430263 | 0.84 | SIGMAR1 (0.50) | KDM4EL3MBTL1TAAR1TRPA1CYP2D6 | |
| SCHEMBL13183502 | 0.84 | ALDH1A1 (0.40) | ALDH1A1TAAR1OPRM1OPRL1MEN1 | |
| SCHEMBL30885596 | 0.82 | KDM4E (0.49) | KDM4EL3MBTL1ALDH1A1TAAR1OPRM1 | |
| SCHEMBL7592231 | 0.79 | TRPA1 (0.44) | KDM4EL3MBTL1ALDH1A1TAAR1TRPA1 | |
| SCHEMBL27796477 | 0.78 | KDM4E (0.46) | KDM4EL3MBTL1TAAR1OPRM1OPRL1 | |
| SCHEMBL4975921 | 0.77 | KDM4E (0.41) | KDM4EL3MBTL1ALDH1A1TAAR1OPRM1 | |
| SCHEMBL2186255 | 0.75 | TRPA1 (0.42) | KDM4EL3MBTL1ALDH1A1TRPA1LMNA | |
| SCHEMBL8473559 | 0.75 | TRPA1 (0.45) | KDM4EL3MBTL1ALDH1A1TAAR1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178937-A2 | ACRYLATED URETHANES, PROCESSES FOR MAKING THE SAME AND CURABLE COMPOSITIONS INCLUDING THE SAME | Henkel Corporation (US) | 2010-04-28 | — | — | EP | claimed |
| WO-2009005835-A2 | ACRYLATED URETHANES, PROCESSES FOR MAKING THE SAME AND CURABLE COMPOSITIONS INCLUDING THE SAME | HENKEL CORPORATION (US) | 2009-01-08 | — | — | WO | claimed |