Sugi Predict

Sugi Predict / Compounds / SCHEMBL2186255

SCHEMBL2186255

SCHEMBL2186255

CC(CO)N(c1ccccc1)C(C)CO

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TRPA1 O75762 4/20 0.42
▸ ALDH1A1 P00352 6/20 0.40
▸ TP53 P04637 2/20 0.40
▸ LMNA P02545 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ KDM4E B2RXH2 3/20 0.38
▸ CHRNB2 P17787 1/20 0.38
▸ CHRNB4 P30926 1/20 0.38
▸ CHRNA3 P32297 1/20 0.38
▸ CHRNA4 P43681 1/20 0.38
▸ GLA P06280 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ APOBEC3A P31941 1/20 0.37
▸ APOBEC3G Q9HC16 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ ALOX12 P18054 1/20 0.36
▸ HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20906284 0.84 TSHR (0.36) TRPA1ALDH1A1TP53LMNASMN1; SMN2
SCHEMBL8473559 0.82 TRPA1 (0.45) TRPA1ALDH1A1TP53LMNASMN1; SMN2
SCHEMBL6832933 0.82 TRPA1 (0.45) TRPA1ALDH1A1TP53LMNASMN1; SMN2
SCHEMBL5376140 0.80 ALDH1A1 (0.41) ALDH1A1TSHRMAPTSLC6A2SLC6A4
SCHEMBL2476976 0.79 ALDH1A1 (0.43) TRPA1ALDH1A1TP53LMNASMN1; SMN2
SCHEMBL6650120 0.78 CHRNB2 (0.41) ALDH1A1TP53LMNASMN1; SMN2CHRNB2
SCHEMBL6649994 0.78 ALOX5 (0.34) ALDH1A1KDM4EPOLBMAPT
SCHEMBL2399628 0.78 ACHE (0.39) ALDH1A1TP53LMNAGLAPOLB
SCHEMBL17046026 0.77 ALDH1A1 (0.42) TRPA1ALDH1A1TP53LMNASMN1; SMN2
SCHEMBL5224483 0.77 AOC3 (0.40) ALDH1A1TP53LMNASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022096808-A1 HYDROCARBON POLYMER WITH POLYETHER AND POLYOLEFIN BLOCKS COMPRISING AT LEAST ONE ALKOXYSILANE END GROUP BOSTIK SA (FR) 2022-05-12 — — WO disclosed
US-11160764-B2 Drug delivery composition containing silyl polymers MEDHERANT LIMITED (GB) 2021-11-02 — — US disclosed
US-10898389-B2 Breathable self-adhesive articles BOSTIK SA (FR) 2021-01-26 — — US disclosed
US-10889717-B2 Compositions, methods, and test kits for determining authenticity MILLIKEN & COMPANY (US) 2021-01-12 — — US disclosed
EP-2825214-B1 BREATHABLE SELF-ADHESIVE ARTICLES BOSTIK SA (FR) 2019-05-01 — — EP disclosed
US-20190112484-A1 COMPOSITIONS, METHODS, AND TEST KITS FOR DETERMINING AUTHENTICITY MILLIKEN & COMPANY 2019-04-18 — — US disclosed
EP-2870214-B1 USE OF AN ADHESIVE COMPOSITION TO PROVIDE A BONDING IN A WET ENVIRONMENT BOSTIK SA (FR) 2019-01-23 — — EP disclosed
US-20180318233-A1 DRUG DELIVERY COMPOSITION CONTAINING SILYL POLYMERS MEDHERANT LIMITED (GB) 2018-11-08 — — US disclosed
EP-3370696-A1 DRUG DELIVERY COMPOSITION CONTAINING SILYL POLYMERS Medherant Limited (GB) 2018-09-12 — — EP disclosed
US-20180208813-A1 POLY(UREA-URETHANE) COMPRISING POLYURETHANE-POLYETHER AND POLYURETHANE-POLYESTER BLOCKS AND AN ALKOXYSILANE END GROUP BOSTIK SA (FR) 2018-07-26 — — US disclosed
EP-0855419-A1 Process for coating polymeric gel ELF ATOCHEM S.A. (FR) 1998-07-29 — — EP disclosed
EP-0822012-A1 Coating on metallic surfaces and use on tubes and cables ELF ATOCHEM S.A. (FR) 1998-02-04 — — EP disclosed
EP-0814487-A1 Impregnants for self-healing capacitors ELF ATOCHEM S.A. (FR) 1997-12-29 — — EP disclosed
EP-0784070-A1 Plasticised compound based on polyalcohol with controlled viscosity ELF ATOCHEM S.A. (FR) 1997-07-16 — — EP disclosed
EP-0743655-A1 Cross-linkable dielectric composition ELF ATOCHEM S.A. (FR) 1996-11-20 — — EP disclosed
EP-0676432-A1 Polyurethane elastomer formulation on the basis of polydiene polyols and castor oil having improved damping properties ELF ATOCHEM S.A. (FR) 1995-10-11 — — EP disclosed
EP-0190333-A4 AN ACTIVE HYDROGEN-CONTAINING COMPOSITION CONTAINING A DIALKANOL TERTIARY AMINE AND A PROCESS FOR PREPARING A POLYURETHANE FOAM. DOW CHEMICAL CO (US) 1987-01-10 — — EP disclosed
US-4632943-A RIGID, SHRINK RESISTANT, RIM DOW CHEMICAL COMPANY (US) 1986-12-30 — — US disclosed
EP-0190333-A1 AN ACTIVE HYDROGEN-CONTAINING COMPOSITION CONTAINING A DIALKANOL TERTIARY AMINE AND A PROCESS FOR PREPARING A POLYURETHANE FOAM THE DOW CHEMICAL COMPANY (US) 1986-08-13 — — EP disclosed
WO-1986001522-A1 AN ACTIVE HYDROGEN-CONTAINING COMPOSITION CONTAINING A DIALKANOL TERTIARY AMINE AND A PROCESS FOR PREPARING A POLYURETHANE FOAM THE DOW CHEMICAL COMPANY (US) 1986-03-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10889717-B2 Compositions, methods, and test kits for determining authenticity AHR, AR, ARSA TRPA1 4055/4885ALDH1A1 586/4885TP53 1867/4885
US-11160764-B2 Drug delivery composition containing silyl polymers ILK, ITGAL, LCP1 TRPA1 225/4885ALDH1A1 1389/4885TP53 3389/4885
US-20180318233-A1 DRUG DELIVERY COMPOSITION CONTAINING SILYL POLYMERS ILK, ITGAL, LCP1 TRPA1 225/4885ALDH1A1 1389/4885TP53 3389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.