Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27732096 | 0.91 | LMNA (0.56) | ALDH1A1MAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL27711774 | 0.91 | LMNA (0.55) | ALDH1A1MAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL27732017 | 0.90 | NAMPT (0.45) | ALDH1A1POLBMAPTSMN1; SMN2KDM4E | |
| SCHEMBL27711759 | 0.90 | LMNA (0.59) | ALDH1A1MAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL27731984 | 0.88 | LMNA (0.53) | ALDH1A1MAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL27731979 | 0.87 | NAMPT (0.49) | ALDH1A1POLBMAPTSMN1; SMN2KDM4E | |
| SCHEMBL4512056 | 0.79 | DGAT1 (0.68) | ALDH1A1POLBMAPTSMN1; SMN2KDM4E | |
| SCHEMBL27732011 | 0.73 | MAPT (0.72) | ALDH1A1MAPTSMN1; SMN2KDM4ENAMPT | |
| SCHEMBL27731982 | 0.73 | MAPT (0.57) | ALDH1A1POLBMAPTSMN1; SMN2KDM4E | |
| SCHEMBL27732014 | 0.72 | MAPT (0.51) | ALDH1A1MAPTSMN1; SMN2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101243058-A | * oxadiazole derivatives as DGAT inhibitors | ASTRAZENECA AB (SE) | 2008-08-13 | — | — | CN | claimed |
| CN-101243058-A | * oxadiazole derivatives as DGAT inhibitors | ASTRAZENECA AB (SE) | 2008-08-13 | — | — | CN | disclosed |