Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27732097 | 0.85 | NAMPT (0.47) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL27711765 | 0.79 | LMNA (0.50) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL4499303 | 0.78 | DGAT1 (0.60) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL27732014 | 0.76 | MAPT (0.51) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL27732011 | 0.75 | MAPT (0.72) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL27731984 | 0.74 | LMNA (0.53) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL27731979 | 0.74 | NAMPT (0.49) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL27731980 | 0.73 | DGAT1 (0.51) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL27732015 | 0.73 | ALDH1A1 (0.48) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL27711759 | 0.73 | LMNA (0.59) | MAPTALDH1A1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101243058-A | * oxadiazole derivatives as DGAT inhibitors | ASTRAZENECA AB (SE) | 2008-08-13 | — | — | CN | claimed |
| CN-101243058-A | * oxadiazole derivatives as DGAT inhibitors | ASTRAZENECA AB (SE) | 2008-08-13 | — | — | CN | disclosed |