SCHEMBL2367569

SCHEMBL2367569

C[Si](C)(C)O[Si](CCCC(O)C(O)CO)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2367736 0.93
Methacrylic Acid SCHEMBL11039926 0.86
SCHEMBL2773252 0.85
SCHEMBL9614390 0.81 THRB (0.34)
SCHEMBL2770385 0.77 LMNA (0.33)
SCHEMBL5837961 0.73 HPGD (0.30)
SCHEMBL2493718 0.73 LMNA (0.35)
SCHEMBL403250 0.72 ALDH1A1 (0.30)
SCHEMBL373856 0.72
SCHEMBL6249836 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
EP-3861039-A1 HYDROGEL COMPOSITIONS Ophtalmic Compagnie (FR) 2021-08-11 EP claimed
WO-2020070423-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2020-04-09 WO claimed
EP-2077292-B1 Polysiloxane-based prepolymer and hydrogel FAR EASTERN NEW CENTURY CORP (TW) 2013-08-14 EP claimed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP disclosed
EP-3861039-A1 HYDROGEL COMPOSITIONS Ophtalmic Compagnie (FR) 2021-08-11 EP disclosed
WO-2020070423-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2020-04-09 WO disclosed
EP-1589367-B1 PHOTOCHROMIC CONTACT LENS EXCELLING IN DECOLORING CHARACTERISTIC MENICON CO LTD (JP) 2019-03-13 EP disclosed
US-8288496-B2 Contact lens and its manufacturing method NIPPON CONTACT LENS INC. (JP) 2012-10-16 US disclosed
US-20110237701-A1 CONTACT LENS AND ITS MANUFACTURING METHOD NIPPON CONTACT LENS INC. (JP) 2011-09-29 US disclosed
EP-2369370-A2 Contact lens and its manufacturing method Nippon Contact Lens Inc. (JP) 2011-09-28 EP disclosed
EP-2174966-A1 OPTICAL MATERIAL AND OPHTHALMIC LENS MADE OF THE SAME Menicon Co., Ltd. (JP) 2010-04-14 EP disclosed
EP-1566684-B1 LENS FOR EYE AND METHOD FOR MARKING THEREOF MENICON CO LTD (JP) 2007-03-14 EP disclosed
US-7044598-B2 Lens for eye and method for marking thereof MENICON CO., LTD.. (JP) 2006-05-16 US disclosed
US-20050243273-A1 Photochromic contact lens having excellent discoloring characteristic MENICON CO., LTD. (JP) 2005-11-03 US disclosed
EP-1589367-A1 PHOTOCHROMIC CONTACT LENS EXCELLING IN DECOLORING CHARACTERISTIC MENICON CO., LTD. (JP) 2005-10-26 EP disclosed
US-20050206843-A1 Lens for eye and method for marking thereof MENICON CO., LTD. (JP) 2005-09-22 US disclosed
EP-1566684-A1 LENS FOR EYE AND METHOD FOR MARKING THEREOF MENICON CO., LTD. (JP) 2005-08-24 EP disclosed
US-4450264-A CROSSLINKED COPOLYMER OF A TRIS/TRIMETHYLSILOXY/SILYL ALKYL OR CYCLOHEXYL ACRYLATE; OXYGEN PERMEABILITY POLYMATIC INVESTMENT CORP., N.V. (NL) 1984-05-22 US disclosed