Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PKLR | P30613 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713188 | 0.90 | CA12 (0.43) | ATMALDH1A1TBXA2RLMNATHRB | |
| SCHEMBL4618946 | 0.82 | SFRP1 (0.64) | ALDH1A1L3MBTL1SFRP1NPSR1 | |
| SCHEMBL19897911 | 0.81 | ATM (0.55) | ATMALDH1A1TBXA2RLMNATHRB | |
| SCHEMBL4619320 | 0.79 | SFRP1 (0.71) | ATMALDH1A1TBXA2RLMNAPKLR | |
| SCHEMBL1200801 | 0.77 | ALDH1A1 (0.75) | ATMALDH1A1TBXA2RLMNAKDM4E | |
| SCHEMBL4617937 | 0.77 | ATM (0.69) | ATMALDH1A1TBXA2RLMNASFRP1 | |
| SCHEMBL4618980 | 0.76 | RAB9A (0.51) | ATMALDH1A1LMNASFRP1KDM4E | |
| Hydrazine SCHEMBL11854301 | 0.75 | ALDH1A1 (0.71) | ATMALDH1A1TBXA2RLMNAKDM4E | |
| SCHEMBL4637627 | 0.74 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1 | |
| SCHEMBL2949015 | 0.74 | FABP4 (0.57) | ATMALDH1A1TBXA2RLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208299-A | Diarylsulfone sulfonamides and use therof | WYETH CORP (US) | 2008-06-25 | — | — | CN | disclosed |