Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733859 | 0.94 | PPARA (0.47) | PPARGPPARDPPARAALDH1A1SMN1; SMN2 | |
| SCHEMBL28775098 | 0.91 | PPARG (0.47) | PPARGPPARDPPARAP2RX3KMT2A | |
| SCHEMBL27733879 | 0.88 | DYRK1A (0.47) | PPARGPPARDP2RX3LMNAMAPT | |
| SCHEMBL27713459 | 0.88 | PPARG (0.36) | PPARGPPARDPPARAMEN1KMT2A | |
| SCHEMBL27733702 | 0.87 | PPARG (0.46) | PPARGPPARDPPARAP2RX3MEN1 | |
| SCHEMBL27733852 | 0.84 | PSEN1 (0.39) | PPARGPPARDPPARA | |
| SCHEMBL27733882 | 0.83 | PPARG (0.38) | PPARGPPARDPPARA | |
| SCHEMBL27733711 | 0.82 | PPARG (0.41) | PPARGPPARDPPARAMEN1KMT2A | |
| SCHEMBL27713509 | 0.82 | AKR1B1 (0.36) | PPARGPPARDPPARAMAPTSMN1; SMN2 | |
| SCHEMBL27733863 | 0.82 | PPARG (0.47) | PPARGPPARDPPARALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |