Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | PPARD | Q03181 | 5/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733680 | 0.91 | PPARG (0.47) | PPARGPPARDPPARANPC1RAB9A | |
| SCHEMBL27733828 | 0.90 | PPARG (0.47) | PPARGPPARDPPARANPC1RAB9A | |
| SCHEMBL27733879 | 0.88 | DYRK1A (0.47) | PPARGPPARDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27733702 | 0.86 | PPARG (0.46) | PPARGPPARDPPARANPC1RAB9A | |
| SCHEMBL27733859 | 0.85 | PPARA (0.47) | PPARGPPARDPPARANPC1RAB9A | |
| SCHEMBL27733863 | 0.84 | PPARG (0.47) | PPARGPPARDPPARAPIK3CGLMNA | |
| SCHEMBL27733852 | 0.83 | PSEN1 (0.39) | PPARGPPARDPPARA | |
| SCHEMBL27733711 | 0.81 | PPARG (0.41) | PPARGPPARDPPARAKDM4EKMT2A | |
| SCHEMBL27833766 | 0.80 | PHGDH (0.38) | PPARGPPARDPPARALMNAKMT2A | |
| SCHEMBL27713459 | 0.80 | PPARG (0.36) | PPARGPPARDPPARARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |