Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | PPARD | Q03181 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733680 | 0.94 | PPARG (0.47) | PPARAPPARGPPARDNPC1RAB9A | |
| SCHEMBL27713509 | 0.88 | AKR1B1 (0.36) | PPARAPPARGPPARDNPC1RAB9A | |
| SCHEMBL28775098 | 0.85 | PPARG (0.47) | PPARAPPARGPPARDNPC1RAB9A | |
| SCHEMBL27733702 | 0.84 | PPARG (0.46) | PPARAPPARGPPARDNPC1RAB9A | |
| SCHEMBL27733852 | 0.84 | PSEN1 (0.39) | PPARAPPARGPPARD | |
| SCHEMBL27733882 | 0.83 | PPARG (0.38) | PPARAPPARGPPARD | |
| SCHEMBL27733879 | 0.82 | DYRK1A (0.47) | PPARGPPARDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27733711 | 0.82 | PPARG (0.41) | PPARAPPARGPPARD | |
| SCHEMBL27713459 | 0.82 | PPARG (0.36) | PPARAPPARGPPARDRAB9ATP53 | |
| SCHEMBL27833766 | 0.81 | PHGDH (0.38) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |