Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 5/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28775091 | 0.89 | PPARG (0.46) | PPARGPPARDPPARAP2RX3NPC1 | |
| SCHEMBL28775099 | 0.88 | PPARG (0.43) | PPARGPPARDPPARANPC1RAB9A | |
| SCHEMBL27733680 | 0.87 | PPARG (0.47) | PPARGPPARDPPARAP2RX3NPC1 | |
| SCHEMBL28775098 | 0.86 | PPARG (0.47) | PPARGPPARDPPARAP2RX3NPC1 | |
| SCHEMBL27733859 | 0.84 | PPARA (0.47) | PPARGPPARDPPARANPC1RAB9A | |
| SCHEMBL27733879 | 0.84 | DYRK1A (0.47) | PPARGPPARDP2RX3NPC1RAB9A | |
| SCHEMBL27733852 | 0.84 | PSEN1 (0.39) | PPARGPPARDPPARAPOLBACLY | |
| SCHEMBL29193361 | 0.82 | PPARG (0.64) | PPARGPPARDPPARAP2RX3NAMPT | |
| SCHEMBL27733711 | 0.82 | PPARG (0.41) | PPARGPPARDPPARAMEN1KMT2A | |
| SCHEMBL27733863 | 0.82 | PPARG (0.47) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |