Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 5/20 | 0.37 |
| ▸ | ACLY | P53396 | 6/20 | 0.34 |
| ▸ | PHGDH | O43175 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713371 | 0.88 | PPARG (0.42) | PPARGPPARAPPARDACLY | |
| SCHEMBL28770822 | 0.86 | RAB9A (0.37) | PPARGPPARAKDM4EPPARDMEN1 | |
| SCHEMBL27733711 | 0.85 | PPARG (0.41) | PPARGPPARAKDM4EPPARDACLY | |
| SCHEMBL27833766 | 0.83 | PHGDH (0.38) | PPARGPPARAPPARDACLYPHGDH | |
| SCHEMBL27733882 | 0.82 | PPARG (0.38) | PPARGPPARAKDM4EPPARDACLY | |
| SCHEMBL27733852 | 0.82 | PSEN1 (0.39) | PPARGPPARAPPARDACLYPHGDH | |
| SCHEMBL28775109 | 0.82 | RECQL (0.39) | PPARGPPARAKDM4EPPARDACLY | |
| SCHEMBL27733674 | 0.77 | CYP3A4 (0.34) | PPARGPPARAKDM4EPPARDACLY | |
| SCHEMBL28770843 | 0.77 | PPARG (0.34) | PPARGPPARAPPARDACLYPHGDH | |
| SCHEMBL27733841 | 0.77 | F7 (0.36) | PPARGPPARAPPARDPHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |