Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 8/20 | 0.34 |
| ▸ | PPARD | Q03181 | 6/20 | 0.34 |
| ▸ | PPARA | Q07869 | 6/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.31 |
| ▸ | ACLY | P53396 | 5/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733852 | 0.81 | PSEN1 (0.39) | PPARGPPARDPPARAACLY | |
| SCHEMBL28775109 | 0.79 | RECQL (0.39) | PPARGPPARDPPARAACLYKDM4E | |
| SCHEMBL27833766 | 0.78 | PHGDH (0.38) | PPARGPPARDPPARAACLY | |
| SCHEMBL27733711 | 0.78 | PPARG (0.41) | PPARGPPARDPPARAACLYKDM4E | |
| SCHEMBL27733726 | 0.77 | PPARG (0.42) | PPARGPPARDPPARAACLYKDM4E | |
| SCHEMBL27733696 | 0.77 | PTGS1 (0.40) | PPARGPPARDPPARA | |
| SCHEMBL27733680 | 0.77 | PPARG (0.47) | PPARGPPARDPPARA | |
| SCHEMBL27733859 | 0.77 | PPARA (0.47) | PPARGPPARDPPARA | |
| SCHEMBL28770822 | 0.76 | RAB9A (0.37) | PPARGPPARDPPARAKDM4E | |
| SCHEMBL27733882 | 0.76 | PPARG (0.38) | PPARGPPARDPPARAACLYKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |