Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.62 |
| ▸ | HTR6 | P50406 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.46 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.46 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.46 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL516500 | 0.96 | HSD11B1 (0.67) | HSD11B1HTR6ALDH1A1HSD17B10TDP1 | |
| SCHEMBL9475449 | 0.89 | HSD11B1 (0.75) | HSD11B1HTR6ALDH1A1KMT2AABCC9 | |
| SCHEMBL2034446 | 0.83 | HSD11B1 (0.68) | HSD11B1ALDH1A1HSD17B10KMT2AABCC9 | |
| SCHEMBL9403464 | 0.83 | HSD11B1 (0.68) | HSD11B1HTR6ALDH1A1KMT2AABCC9 | |
| SCHEMBL2123876 | 0.82 | HSD11B1 (0.59) | HSD11B1ALDH1A1HSD17B10KMT2AAKR1B1 | |
| SCHEMBL248010 | 0.82 | HSD11B1 (0.59) | HSD11B1ALDH1A1HSD17B10KMT2AAKR1B1 | |
| SCHEMBL30697126 | 0.82 | HSD11B1 (0.59) | HSD11B1ALDH1A1HSD17B10KMT2AAKR1B1 | |
| SCHEMBL362886 | 0.82 | MCOLN3 (0.53) | HSD11B1HTR6KMT2AAKR1B1TSHR | |
| SCHEMBL3444895 | 0.80 | HSD11B1 (0.65) | HSD11B1ALDH1A1KMT2AABCC9ABCC8 | |
| SCHEMBL9370273 | 0.80 | HSD11B1 (0.59) | HSD11B1HTR6ALDH1A1HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208299-A | Diarylsulfone sulfonamides and use therof | WYETH CORP (US) | 2008-06-25 | — | — | CN | disclosed |