Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.75 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.53 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.53 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.53 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 3/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2034446 | 0.94 | HSD11B1 (0.68) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9403464 | 0.94 | HSD11B1 (0.68) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL516500 | 0.93 | HSD11B1 (0.67) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL28543840 | 0.90 | HSD11B1 (0.69) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8867078 | 0.90 | HSD11B1 (0.64) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9475086 | 0.90 | HSD11B1 (0.64) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9635238 | 0.90 | HSD11B1 (0.65) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL3444895 | 0.90 | HSD11B1 (0.65) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL27733744 | 0.89 | HSD11B1 (0.62) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9756792 | 0.88 | HSD11B1 (0.62) | HSD11B1ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179193-A | From dihaloaromatic sulfone, polyhalodiarylsulfone and polymerizable sulfur source; coatings, films, moldings, fibers | PHILLIPS PETROLEUM COMPANY (US) | 1993-01-12 | — | — | US | claimed |
| US-5177174-A | Branched aromatic sulfide/sulfone polymer production | PHILLIPS PETROLEUM COMPANY (US) | 1993-01-05 | — | — | US | claimed |
| US-5179193-A | From dihaloaromatic sulfone, polyhalodiarylsulfone and polymerizable sulfur source; coatings, films, moldings, fibers | PHILLIPS PETROLEUM COMPANY (US) | 1993-01-12 | — | — | US | disclosed |