SCHEMBL516500

SCHEMBL516500

O=S(=O)(c1ccccc1)c1ccccc1Cl

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 4/20 0.67
HTR6 P50406 5/20 0.57
KMT2A Q03164 2/20 0.50
ABCC9 O60706 1/20 0.48
ABCC8 Q09428 1/20 0.48
KCNJ11 Q14654 1/20 0.48
KCNJ8 Q15842 1/20 0.48
AKR1B1 P15121 1/20 0.47
TSHR P16473 1/20 0.47
HTT P42858 1/20 0.47
ALDH1A1 P00352 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
KIF18A Q8NI77 1/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
GFER P55789 1/20 0.46
CNR2 P34972 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27733744 0.96 HSD11B1 (0.62) HSD11B1HTR6KMT2AABCC9ABCC8
SCHEMBL9475449 0.93 HSD11B1 (0.75) HSD11B1HTR6KMT2AABCC9ABCC8
SCHEMBL2034446 0.87 HSD11B1 (0.68) HSD11B1KMT2AABCC9ABCC8KCNJ11
SCHEMBL9403464 0.87 HSD11B1 (0.68) HSD11B1HTR6KMT2AABCC9ABCC8
SCHEMBL248010 0.85 HSD11B1 (0.59) HSD11B1KMT2AAKR1B1TSHRALDH1A1
SCHEMBL2123876 0.85 HSD11B1 (0.59) HSD11B1KMT2AAKR1B1TSHRALDH1A1
SCHEMBL30697126 0.85 HSD11B1 (0.59) HSD11B1KMT2AAKR1B1TSHRALDH1A1
SCHEMBL362886 0.85 MCOLN3 (0.53) HSD11B1HTR6KMT2AAKR1B1TSHR
SCHEMBL3444895 0.84 HSD11B1 (0.65) HSD11B1KMT2AABCC9ABCC8KCNJ11
SCHEMBL8867078 0.84 HSD11B1 (0.64) HSD11B1HTR6KMT2AABCC9ABCC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2414430-B2 METHOD FOR PRODUCING LOW-CHLORINE POLYBIPHENYL SULFONE POLYMERS BASF SE (DE) 2023-09-13 EP claimed
EP-2414430-B1 METHOD FOR PRODUCING LOW-CHLORINE POLYBIPHENYL SULFONE POLYMERS BASF SE (DE) 2017-10-04 EP claimed
US-9765185-B2 High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2017-09-19 US claimed
US-9340496-B2 Process for the production of a sulfone monomer BANDODKAR HEMANT RATANAKAR (IN) 2016-05-17 US claimed
US-9133111-B2 High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2015-09-15 US claimed
US-20150126701-A1 METHOD FOR THE PRODUCTION OF POLYSULFONES, AND POLYSULFONES EMS-PATENT AG (CH) 2015-05-07 US claimed
US-20140302992-A1 COMPOSITION, USES AND PREPARATION PROCESS THEREOF, AS WELL AS METHOD TO ENSURE HIGH CORN CROP YIELD FMC QUIMICA DO BRASIL, LTDA. (BR) 2014-10-09 US claimed
US-20140221595-A1 HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) SOLVAY ADVANCED POLYMERS, LLC (US) 2014-08-07 US claimed
EP-2762003-A1 AGROCHEMICAL COMPOSITION, USES THEREOF AND PROCESS FOR PREPARING SAME, AS WELL AS A METHOD FOR ENSURING HIGH PRODUCTIVITY OF CROPS FMC Quimica Do Brasil LTDA. (BR) 2014-08-06 EP claimed
EP-2342260-B1 HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) SOLVAY SPECIALTY POLYMERS USA (US) 2014-07-23 EP claimed
US-20070066741-A1 High glass transition temperature thermoplastic articles CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 US claimed
EP-1660556-A1 COPOLYETHERIMIDES GENERAL ELECTRIC COMPANY (US) 2006-05-31 EP claimed
WO-2005023901-A1 COPOLYETHERIMIDES GENERAL ELECTRIC COMPANY (US) 2005-03-17 WO claimed
US-6849706-B1 Copolyetherimides GENERAL ELECTRIC COMPANY (US) 2005-02-01 US claimed
US-5288848-A Reacting mono- and dihalogenated aromatics with alkali sulfide ; low corrosion during processing BAYER AKTIENGESELLSCHAFT (DE) 1994-02-22 US claimed
EP-0214471-B1 PROCESS FOR THE PREPARATION OF HIGH MOLECULAR WEIGHT POLYARYLENE SULFIDES WHICH CAN BE RETICULATED BAYER AG (DE) 1990-11-28 EP claimed
EP-0279387-B1 PROCESS FOR THE SEPARATION OF 4,4'-DICHLORODIPHENYL SULFONE BASF Aktiengesellschaft (DE) 1990-05-02 EP claimed
US-4855388-A PREVENTING MOLECULAR WEIGHT DEGRADATION AMOCO CORPORATION (US) 1989-08-08 US claimed
US-4774311-A FLUORIDE CATALYSTS AMOCO CORPORATION (US) 1988-09-27 US claimed
EP-0211693-A1 Preparation of poly(aryl ether ketones) AMOCO CORPORATION (US) 1987-02-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140221595-A1 HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) DHPS, PKM, PCBP1 HSD11B1 1421/4885HTR6 2956/4885KMT2A 1332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.