SCHEMBL2034446

SCHEMBL2034446

O=S(=O)(c1ccc(Cl)cc1)c1ccccc1Cl

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 4/20 0.68
ALDH1A1 P00352 2/20 0.60
CYP3A4 P08684 1/20 0.60
MAPK1 P28482 1/20 0.60
CNR2 P34972 2/20 0.51
KDM4E B2RXH2 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
PKM P14618 1/20 0.50
ABCC9 O60706 1/20 0.49
ABCC8 Q09428 1/20 0.49
KCNJ11 Q14654 1/20 0.49
KCNJ8 Q15842 1/20 0.49
POLB P06746 1/20 0.49
MAPT P10636 1/20 0.48
KIF18A Q8NI77 1/20 0.47
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46
CA12 O43570 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL28495365 0.94 HSD11B1 (0.63) HSD11B1ALDH1A1CYP3A4MAPK1CNR2
SCHEMBL9475449 0.94 HSD11B1 (0.75) HSD11B1ALDH1A1CYP3A4MAPK1CNR2
SCHEMBL10396332 0.89 HSD11B1 (0.57) HSD11B1ALDH1A1CYP3A4MAPK1CNR2
SCHEMBL10869745 0.89 ALDH1A1 (0.68) HSD11B1ALDH1A1CYP3A4MAPK1CNR2
SCHEMBL9403464 0.88 HSD11B1 (0.68) HSD11B1ALDH1A1CYP3A4MAPK1CNR2
SCHEMBL516500 0.87 HSD11B1 (0.67) HSD11B1ALDH1A1CNR2KMT2AABCC9
SCHEMBL3444895 0.84 HSD11B1 (0.65) HSD11B1ALDH1A1CNR2MEN1KMT2A
SCHEMBL8867078 0.84 HSD11B1 (0.64) HSD11B1ALDH1A1CYP3A4CNR2MEN1
SCHEMBL28543840 0.84 HSD11B1 (0.69) HSD11B1ALDH1A1CNR2KDM4EABCC9
SCHEMBL9635238 0.84 HSD11B1 (0.65) HSD11B1CNR2PKMABCC9ABCC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220371993-A1 (C)CRYSTAL COMPOSITION (CC) COMPRISING 4,4'-DICHLORODIPHENYLSULFONE CRYSTALS (C) BASF SE (DE) 2022-11-24 US claimed
EP-3914584-B1 (C)CRYSTAL COMPOSITION (CC) COMPRISING 4,4'-DICHLORODIPHENYLSULFONE CRYSTALS (C) BASF SE (DE) 2022-10-12 EP claimed
EP-3914584-A1 (C)CRYSTAL COMPOSITION (CC) COMPRISING 4,4'-DICHLORODIPHENYLSULFONE CRYSTALS (C) BASF SE (DE) 2021-12-01 EP claimed
WO-2021037797-A1 (C)CRYSTAL COMPOSITION (CC) COMPRISING 4,4'-DICHLORODIPHENYLSULFONE CRYSTALS (C) BASF SE (DE) 2021-03-04 WO claimed
US-9434199-B2 Thermal recording material FINE ACE CORPORATION (JP) 2016-09-06 US claimed
US-20150051070-A1 THERMAL RECORDING MATERIAL FINE ACE CORPORATION (JP) 2015-02-19 US claimed
EP-2829409-A1 THERMAL RECORDING MATERIAL Fine Ace Corporation (JP) 2015-01-28 EP claimed
US-20110218357-A1 PROCESSES FOR PREPARING 4-CHLOROBENZENESULFONIC ACID AND 4,4'-DICHLORODIPHENYL SULFONE BASF SE (DE) 2011-09-08 US claimed
EP-0279387-B1 PROCESS FOR THE SEPARATION OF 4,4'-DICHLORODIPHENYL SULFONE BASF Aktiengesellschaft (DE) 1990-05-02 EP claimed
US-4876390-A ADSORPTION USING TYPE X OR TYPE ZEOLITE UOP (US) 1989-10-24 US claimed
US-4873372-A Isolation of 4,4'-dichlorodiphenyl sulfone BASF AKTIENGESELLSCHAFT (DE) 1989-10-10 US claimed
US-4110314-A Process for preparing an aromatic polymer in the presence of an inert nonpolar aromatic reaction lubricant DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1978-08-29 US claimed
JP-58008506-A None JP disclosed
EP-4433524-B1 POLYARYLETHER COPOLYMERS BASED ON DIOL SUGAR ALCOHOLS BASF SE (DE) 2025-10-15 EP disclosed
US-20250043074-A1 POLYARYLETHER COPOLYMERS BASED ON DIOL SUGAR ALCOHOLS BASF SE (DE) 2025-02-06 US disclosed
EP-4433524-A1 POLYARYLETHER COPOLYMERS BASED ON DIOL SUGAR ALCOHOLS BASF SE (DE) 2024-09-25 EP disclosed
US-4482742-A CATALYTIC REDUCING AND DEHALOGENATION 3,3*-DINTITRODIPHENYLSULFONE MITSUI TOATSU CHEMICALS INC. (JP) 1984-11-13 US disclosed
US-4451640-A Process for producing aromatic sulfide polymer KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-05-29 US disclosed
JP-S588506-A SELECTIVE SEPARATION MEMBRANE TOYOBO CO LTD 1983-01-18 JP disclosed
US-4110314-A Process for preparing an aromatic polymer in the presence of an inert nonpolar aromatic reaction lubricant DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1978-08-29 US disclosed