Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733771 | 0.92 | HTR6 (0.46) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27713331 | 0.88 | HTR6 (0.48) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27641191 | 0.77 | HTR6 (0.53) | HTR6MEN1KMT2A | |
| SCHEMBL3362896 | 0.76 | HTR6 (0.44) | HTR6 | |
| SCHEMBL27733781 | 0.76 | KLK7 (0.47) | HTR6MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27713337 | 0.75 | HTR6 (0.48) | HTR6MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27713443 | 0.75 | AKR1C3 (0.48) | HTR6MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27713312 | 0.74 | SMN1; SMN2 (0.49) | HTR6MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL28770869 | 0.74 | LMNA (0.56) | HTR6MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27733689 | 0.73 | ELANE (0.47) | HTR6MEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |