Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.60 |
| ▸ | FEN1 | P39748 | 1/20 | 0.60 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.51 |
| ▸ | WNT3A | P56704 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29639746 | 1.00 | ERCC5 (0.60) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL30089517 | 0.84 | CTNNB1 (0.68) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL8735550 | 0.84 | ERCC5 (0.74) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL15979740 | 0.84 | CTNNB1 (0.68) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL10770139 | 0.83 | ESR1 (0.46) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL3704844 | 0.82 | ERCC5 (0.60) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL364889 | 0.82 | ERCC5 (0.60) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL31901342 | 0.82 | ERCC5 (0.60) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL8053673 | 0.80 | ERCC5 (0.58) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL168885 | 0.80 | ERCC5 (0.58) | ERCC5FEN1CTNNB1WNT3AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116715671-A | Application of alpha-chromene spiropiperidine compound in preparation of 5-hydroxytryptamine 2C receptor agonist | 苏州大学 | 2023-09-08 | — | — | CN | disclosed |
| US-11649218-B2 | C-Abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-05-16 | — | — | US | disclosed |
| CN-115068475-A | Application of alpha-chromene spiropiperidine compounds in preparation of 5-hydroxytryptamine 2C receptor agonists | 苏州大学 | 2022-09-20 | — | — | CN | disclosed |
| US-9950999-B2 | Non-ionic low diffusing photo-acid generators | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2018-04-24 | — | — | US | disclosed |
| US-9950999-B2 | Non-ionic low diffusing photo-acid generators | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2018-04-24 | — | — | US | disclosed |
| US-9950999-B2 | Non-ionic low diffusing photo-acid generators | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2018-04-24 | — | — | US | disclosed |
| US-20180044284-A1 | NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2018-02-15 | — | — | US | disclosed |
| US-20180044284-A1 | NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2018-02-15 | — | — | US | disclosed |
| US-20180044284-A1 | NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2018-02-15 | — | — | US | disclosed |
| US-20160166526-A1 | COMPOUNDS FOR SUPPRESSING A PERIPHERAL NERVE DISORDER INDUCED BY AN ANTI-CANCER AGENT | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-06-16 | — | — | US | disclosed |
| EP-1875926-A1 | STABLE EMULSION COMPOSITION | Takeda Pharmaceutical Company Limited (JP) | 2008-01-09 | — | — | EP | disclosed |
| WO-2007140183-A1 | FXR AGONISTS | ELI LILLY AND COMPANY (US) | 2007-12-06 | — | — | WO | disclosed |
| US-7247653-B2 | Pharmaceutical composition | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-07-24 | — | — | US | disclosed |
| WO-2007016525-A2 | PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF COMPLEX DISEASES AND THEIR DELIVERY BY INSERTABLE MEDICAL DEVICES | RESVERLOGIX CORP. (CA) | 2007-02-08 | — | — | WO | disclosed |
| WO-2006095885-A1 | ANTIREFLECTIVE FILM, METHOD OF MANUFUCTURING ANTIREFLECTIVE FILM, POLARIZING PLATE AND IMAGE DISPLAY DEVICE USING THE SAME | FUJIFILM CORPORATION (JP) | 2006-09-14 | — | — | WO | disclosed |
| CN-1768050-A | Benzopyran compounds for the treatment of inflammation | PHARMACIA CORP (US) | 2006-05-03 | — | — | CN | disclosed |
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5840895-A | INTERMEDIATES FOR ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649218-B2 | C-Abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same | ABL1, ABL2, MUSK | ERCC5 4649/4885FEN1 4077/4885CTNNB1 1943/4885 |
| US-20160166526-A1 | COMPOUNDS FOR SUPPRESSING A PERIPHERAL NERVE DISORDER INDUCED BY AN ANTI-CANCER AGENT | PMP22, GAP43, NGF | ERCC5 1582/4885FEN1 1824/4885CTNNB1 3967/4885 |
| US-20180044284-A1 | NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS | PLG, PPARG, PKLR | ERCC5 983/4885FEN1 4572/4885CTNNB1 3143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.