Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29360475 | 0.86 | TDP1 (0.60) | TDP1HPGDNPC1RAB9APARP1 | |
| SCHEMBL570920 | 0.86 | TDP1 (0.60) | TDP1HPGDNPC1RAB9APARP1 | |
| Ammonia Solution, Strong SCHEMBL27753074 | 0.84 | TDP1 (0.59) | TDP1HPGDNPC1RAB9AADRB2 | |
| Hydrochloric Acid SCHEMBL28864124 | 0.84 | L3MBTL1 (0.59) | TDP1HPGDNPC1RAB9AADRB2 | |
| SCHEMBL31316346 | 0.84 | PARP1 (0.61) | TDP1HPGDNPC1RAB9APARP1 | |
| SCHEMBL4188727 | 0.84 | PARP1 (0.61) | TDP1HPGDNPC1RAB9APARP1 | |
| SCHEMBL16174807 | 0.83 | HPGD (0.53) | TDP1HPGDNPC1RAB9APARP1 | |
| SCHEMBL9666128 | 0.82 | LMNA (0.56) | TDP1NPC1RAB9AALDH1A1MAPK1 | |
| Ethylene Glycol SCHEMBL28453593 | 0.81 | PARP1 (0.53) | TDP1HPGDNPC1RAB9APARP1 | |
| SCHEMBL7943889 | 0.80 | GPR17 (0.56) | TDP1NPC1RAB9AADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101386590-A | Pyrrolidone containing hydroxymethyl and carboxyl, preparation method and medicament composition and use thereof | INST MATERIA MEDICA CAMS (CN) | 2009-03-18 | — | — | CN | claimed |
| CN-101386590-A | Pyrrolidone containing hydroxymethyl and carboxyl, preparation method and medicament composition and use thereof | INST MATERIA MEDICA CAMS (CN) | 2009-03-18 | — | — | CN | disclosed |