Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 4/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL9435110 | 0.89 | ALDH1A1 (0.41) | ALDH1A1TSHRGABBR2GABBR1CYP1A2 | |
| Phosphoric Acid Monomethyl Ester SCHEMBL27549148 | 0.86 | ALDH1A1 (0.44) | ALDH1A1TSHRGABBR2GABBR1CYP1A2 | |
| Phosphoric Acid Monomethyl Ester SCHEMBL27549147 | 0.86 | ALDH1A1 (0.44) | ALDH1A1TSHRGABBR2GABBR1CYP1A2 | |
| Alcohol SCHEMBL7622017 | 0.80 | PPARD (0.39) | ALDH1A1TSHRPPARDFDPS | |
| Methylamine SCHEMBL28070982 | 0.80 | — | — | |
| SCHEMBL28223995 | 0.80 | CA2 (0.43) | ALDH1A1TSHRLMNABLMCYP3A4 | |
| SCHEMBL47754 | 0.80 | — | — | |
| 1,6-Hexanediol SCHEMBL27938908 | 0.79 | LMNA (0.39) | ALDH1A1TSHRLMNACYP3A4PPARD | |
| Alcohol SCHEMBL26929125 | 0.78 | PPARD (0.37) | ALDH1A1TSHRPPARDFDPS | |
| Methyl Phosphonate SCHEMBL28529800 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240010812-A1 | FLAME-RETARDANT PULVERULENT COMPOSITION AND 3D-PRINTED OBJECT OBTAINED FROM THE SAME | STRATASYS, INC. | 2024-01-11 | — | — | US | disclosed |
| EP-4247618-A1 | FLAME-RETARDANT PULVERULENT COMPOSITION AND 3D-PRINTED OBJECT OBTAINED FROM THE SAME | BASF SE (DE) | 2023-09-27 | — | — | EP | disclosed |
| EP-3564299-B1 | FLAME RETARDANT POLYOLEFIN ARTICLES | BASF SE (DE) | 2023-09-06 | — | — | EP | disclosed |
| CN-116648356-A | Flame-retardant powdery composition and 3D printed object obtained from same | 巴斯夫欧洲公司 | 2023-08-25 | — | — | CN | disclosed |
| WO-2022106402-A1 | FLAME-RETARDANT PULVERULENT COMPOSITION AND 3D-PRINTED OBJECT OBTAINED FROM THE SAME | BASF SE (DE) | 2022-05-27 | — | — | WO | disclosed |
| EP-3924680-A1 | MATTRESS ASSEMBLIES INCLUDING AT LEAST ONE PANEL INCLUDING PHASE CHANGE MATERIALS | Dreamwell, Ltd. (US) | 2021-12-22 | — | — | EP | disclosed |
| US-11058228-B2 | Fire resistant panel including vertically oriented fire retardant treated fibers and an adaptive covering material | DREAMWELL, LTD. (US) | 2021-07-13 | — | — | US | disclosed |
| WO-2020168040-A1 | MATTRESS ASSEMBLIES INCLUDING AT LEAST ONE PANEL INCLUDING PHASE CHANGE MATERIALS | DREAMWELL, LTD. (US) | 2020-08-20 | — | — | WO | disclosed |
| US-20200260882-A1 | MATTRESS ASSEMBLIES INCLUDING AT LEAST ONE PANEL INCLUDING PHASE CHANGE MATERIALS | ECLIPSE BUSINESS CAPITAL LLC, AS ADMINISTRATIVE AGENT | 2020-08-20 | — | — | US | disclosed |
| US-20200254740-A1 | FLAME RESISTANT COMPOSITE FABRIC | BROOKWOOD COMPANIES INCORPORATED | 2020-08-13 | — | — | US | disclosed |
| EP-2670790-A2 | METHODS OF FLAME RETARDING POLYETHYLENE PROCESSED AT HIGH TEMPERATURES | BASF SE (DE) | 2013-12-11 | — | — | EP | disclosed |
| US-20120225980-A1 | METHODS OF FLAME RETARDING POLYETHYLENE PROCESSED AT HIGH TEMPERATURES | BASF SE (DE) | 2012-09-06 | — | — | US | disclosed |
| WO-2012106073-A2 | METHODS OF FLAME RETARDING POLYETHYLENE PROCESSED AT HIGH TEMPERATURES | BASF SE (DE) | 2012-08-09 | — | — | WO | disclosed |
| US-20120183695-A1 | Methods, Systems, and Compositions for Fire Retarding Substrates | PIANA ANDREA (US) | 2012-07-19 | — | — | US | disclosed |
| US-20100173084-A1 | Methods, Systems, and Compositions for Fire Retarding Substrates | TINTORIA PIANA U.S., INC. | 2010-07-08 | — | — | US | disclosed |
| US-7736696-B2 | Methods, systems, and compositions for fire retarding substrates | TINTORIA PIANA U.S., INC. (US) | 2010-06-15 | — | — | US | disclosed |
| US-20070231531-A1 | Methods, Systems, and Compositions for Fire Retarding Substrates | TINTORIA PIANA U.S., INC. | 2007-10-04 | — | — | US | disclosed |
| US-7211293-B2 | Methods, systems and compositions for fire retarding substrates | Gaston International, Inc. (US) | 2007-05-01 | — | — | US | disclosed |
| US-20040121114-A1 | Methods, systems and compositions for fire retarding substrates | NEWORLD FIBERS, LLC | 2004-06-24 | — | — | US | disclosed |
| WO-2004050980-A1 | METHODS, SYSTEMS AND COMPOSITIONS FOR FIRE RETARDING SUBSTRATES | NEWORLD FIBERS, LLC (US) | 2004-06-17 | — | — | WO | disclosed |