Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27735688 | 0.86 | ELANE (0.41) | L3MBTL1ELANEMEN1KMT2ALMNA | |
| SCHEMBL27714808 | 0.84 | ELANE (0.40) | L3MBTL1ELANEMEN1KMT2AKDM4E | |
| SCHEMBL1638661 | 0.75 | L3MBTL1 (0.53) | L3MBTL1ELANEMEN1KMT2ALMNA | |
| SCHEMBL27735638 | 0.75 | GSK3A (0.40) | L3MBTL1ELANEMEN1KMT2AFAAH | |
| SCHEMBL13078704 | 0.72 | KDM4E (0.45) | L3MBTL1ELANEMEN1KMT2ALMNA | |
| SCHEMBL20551423 | 0.71 | L3MBTL1 (0.54) | L3MBTL1ELANEMEN1KMT2AKDM4E | |
| SCHEMBL20552850 | 0.71 | L3MBTL1 (0.63) | L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL2178657 | 0.71 | L3MBTL1 (0.51) | L3MBTL1ELANEMEN1KMT2APTGDR2 | |
| SCHEMBL17771852 | 0.71 | L3MBTL1 (0.44) | L3MBTL1ELANEMEN1KMT2AKDM4E | |
| SCHEMBL13562830 | 0.70 | L3MBTL1 (0.67) | L3MBTL1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101242839-B | Azaindazole compounds and methods of use | CHEMOCENTRYX INC | 2012-11-07 | — | — | CN | disclosed |
| CN-101242839-A | Azaindazole compounds and methods of use | CHEMOCENTRYX INC (US) | 2008-08-13 | — | — | CN | disclosed |