Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27735636 | 0.86 | L3MBTL1 (0.46) | ELANEMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL27714808 | 0.82 | ELANE (0.40) | ELANEMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL27735638 | 0.78 | GSK3A (0.40) | ELANEMEN1KMT2AL3MBTL1GSK3A | |
| SCHEMBL27735648 | 0.76 | HSD17B10 (0.35) | MEN1KMT2AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL1639394 | 0.74 | MEN1 (0.53) | MEN1KMT2AL3MBTL1SMN1; SMN2RECQL | |
| SCHEMBL12726462 | 0.70 | L3MBTL1 (0.40) | ELANEFEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1639426 | 0.70 | KDM4E (0.44) | MEN1KMT2AFEN1L3MBTL1GSK3B | |
| SCHEMBL1639832 | 0.70 | ALOX15 (0.43) | ELANEFEN1L3MBTL1 | |
| SCHEMBL27714800 | 0.68 | ALDH1A1 (0.43) | ELANEMEN1KMT2AFEN1L3MBTL1 | |
| SCHEMBL10063584 | 0.68 | FEN1 (0.44) | ELANEFEN1L3MBTL1GSK3BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101242839-A | Azaindazole compounds and methods of use | CHEMOCENTRYX INC (US) | 2008-08-13 | — | — | CN | disclosed |