Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KDM4A | O75164 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM6A | O15550 | 1/20 | 0.34 |
| ▸ | TET3 | O43151 | 1/20 | 0.34 |
| ▸ | KDM4B | O94953 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.34 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27735636 | 0.84 | L3MBTL1 (0.46) | ELANEKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL27735688 | 0.82 | ELANE (0.41) | ELANEKDM4EKDM4AKDM4CMEN1 | |
| SCHEMBL1638662 | 0.75 | CYP2C19 (0.49) | ELANEKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL13079006 | 0.73 | KDM4E (0.47) | ELANEKDM4EKDM4AKDM4CCNR1 | |
| SCHEMBL3747599 | 0.72 | ELANE (0.43) | ELANEKDM4EKDM4AKDM4CL3MBTL1 | |
| SCHEMBL13885709 | 0.71 | KDM5A (0.41) | ELANEKDM4CL3MBTL1KDM4DGSK3B | |
| SCHEMBL27735638 | 0.71 | GSK3A (0.40) | ELANEKDM4EKDM4AKDM4CMEN1 | |
| SCHEMBL29587624 | 0.71 | POLB (0.41) | ELANEKDM4E | |
| SCHEMBL20530284 | 0.71 | MEN1 (0.37) | ELANEKDM4EMEN1KMT2A | |
| SCHEMBL2883080 | 0.71 | POLB (0.41) | ELANEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101242839-B | Azaindazole compounds and methods of use | CHEMOCENTRYX INC | 2012-11-07 | — | — | CN | disclosed |
| CN-101242839-A | Azaindazole compounds and methods of use | CHEMOCENTRYX INC (US) | 2008-08-13 | — | — | CN | disclosed |