Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 9/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27714803 | 0.85 | MAOB (0.39) | MAOBELANEKDM4EBRD4MEN1 | |
| SCHEMBL27735688 | 0.78 | ELANE (0.41) | GSK3AGSK3BELANEKDM4EL3MBTL1 | |
| SCHEMBL27735636 | 0.75 | L3MBTL1 (0.46) | GSK3AGSK3BMAOBELANEKDM4E | |
| SCHEMBL1639229 | 0.74 | GAA (0.47) | MAOBKDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL27714808 | 0.71 | ELANE (0.40) | GSK3AGSK3BELANEKDM4EL3MBTL1 | |
| SCHEMBL12726405 | 0.70 | MAOB (0.39) | GSK3AGSK3BMAOBELANEMEN1 | |
| SCHEMBL1637819 | 0.69 | ALOX15 (0.42) | KDM4E | |
| SCHEMBL28372779 | 0.64 | HPSE (0.40) | ELANEKDM4EKMT2A | |
| SCHEMBL1638885 | 0.63 | MEN1 (0.47) | MAOBL3MBTL1MEN1KMT2A | |
| SCHEMBL27746408 | 0.63 | ALDH1A1 (0.36) | ELANEKDM4EL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101242839-B | Azaindazole compounds and methods of use | CHEMOCENTRYX INC | 2012-11-07 | — | — | CN | disclosed |
| CN-101242839-A | Azaindazole compounds and methods of use | CHEMOCENTRYX INC (US) | 2008-08-13 | — | — | CN | disclosed |