Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.75 |
| ▸ | EGFR | P00533 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | APP | P05067 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinromide SCHEMBL35056 | 0.86 | SLC6A19 (1.00) | SLC6A19ALDH1A1KMT2AMAPTHTT | |
| Cinromide SCHEMBL35055 | 0.86 | SLC6A19 (1.00) | SLC6A19ALDH1A1KMT2AMAPTHTT | |
| SCHEMBL27542057 | 0.85 | MMP1 (0.66) | EGFRHPGDAPPKMT2ACYP1A2 | |
| N-Butylcinnamamide SCHEMBL3688039 | 0.83 | EGFR (0.88) | EGFRAPPKMT2AMAPTHTT | |
| N-Butylcinnamamide SCHEMBL6231267 | 0.83 | EGFR (0.88) | EGFRAPPKMT2AMAPTHTT | |
| SCHEMBL8756506 | 0.80 | EGFR (0.73) | EGFRHPGDAPPKMT2ACYP1A2 | |
| SCHEMBL8756520 | 0.80 | EGFR (0.73) | EGFRHPGDAPPKMT2ACYP1A2 | |
| SCHEMBL8757222 | 0.80 | EGFR (0.73) | EGFRHPGDAPPKMT2ACYP1A2 | |
| SCHEMBL8757229 | 0.80 | EGFR (0.73) | EGFRHPGDAPPKMT2ACYP1A2 | |
| SCHEMBL8756511 | 0.80 | EGFR (0.73) | EGFRHPGDAPPKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101274901-B | Synthetic method for (E)-3-aryl-2-acrylic amide compound | UNIV ZHEJIANG | 2010-06-23 | — | — | CN | disclosed |
| CN-101274901-A | Synthetic method for (E)-3-aryl-2-acrylic amide compound | UNIV ZHEJIANG (CN) | 2008-10-01 | — | — | CN | disclosed |