Cinromide

Cinromide

SCHEMBL35056

CCNC(=O)C=Cc1cccc(Br)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A19 Q695T7 1/20 1.00
ALDH1A1 P00352 2/20 0.62
HSD17B3 P37058 1/20 0.61
MAPT P10636 1/20 0.61
HTT P42858 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
BACE1 P56817 1/20 0.57
GLA P06280 1/20 0.56
MAOB P27338 4/20 0.54
MAOA P21397 3/20 0.54
PLAAT5 Q96KN8 1/20 0.52
PLAAT4 Q9UL19 1/20 0.52
PKM P14618 1/20 0.51
MEN1 O00255 1/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
KMT2A Q03164 1/20 0.51
KDM4E B2RXH2 1/20 0.51
MAPK1 P28482 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cinromide SCHEMBL35055 1.00 SLC6A19 (1.00) SLC6A19ALDH1A1HSD17B3MAPTHTT
SCHEMBL27735722 0.86 SLC6A19 (0.75) SLC6A19ALDH1A1HSD17B3MAPTHTT
SCHEMBL11257545 0.84 SLC6A19 (0.72) SLC6A19ALDH1A1HSD17B3MAPTHTT
SCHEMBL11257542 0.84 SLC6A19 (0.72) SLC6A19ALDH1A1HSD17B3MAPTHTT
SCHEMBL11257541 0.84 SLC6A19 (0.72) SLC6A19ALDH1A1HSD17B3MAPTHTT
SCHEMBL8740836 0.83 SLC6A19 (0.71) SLC6A19
SCHEMBL8740838 0.83 SLC6A19 (0.71) SLC6A19
SCHEMBL8740837 0.83 SLC6A19 (0.71) SLC6A19
SCHEMBL12426058 0.82 HSD17B3 (0.71) SLC6A19ALDH1A1HSD17B3MAPTHTT
SCHEMBL14244643 0.82 HSD17B3 (0.71) SLC6A19ALDH1A1HSD17B3MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2560634-A1 NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS Piramal Enterprises Limited (IN) 2013-02-27 EP claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 US claimed
US-20110263526-A1 Nitric Oxide Releasing Prodrugs of Therapeutic Agents PIRAMAL LIFE SCIENCES LIMITED (IN) 2011-10-27 US claimed
WO-2011132171-A1 NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS PIRAMAL LIFE SCIENCES LIMITED (IN) 2011-10-27 WO claimed
CN-101484152-A Therapeutic combination for painful medical conditions SANOL ARZNEI SCHWARZ GMBH (DE) 2009-07-15 CN claimed
EP-2026788-A1 THERAPEUTIC COMBINATION FOR PAINFUL MEDICAL CONDITIONS SCHWARZ PHARMA AG (DE) 2009-02-25 EP claimed
WO-2007141018-A1 THERAPEUTIC COMBINATION FOR PAINFUL MEDICAL CONDITIONS SCHWARZ PHARMA AG (DE) 2007-12-13 WO claimed
US-20070042969-A1 Combination therapy for pain in painful diabetic neuropathy SRZ PROPERTIES, INC. (US) 2007-02-22 US claimed
US-20070043120-A1 Therapeutic combination for painful medical conditions UCB PHARMA GMBH (DE) 2007-02-22 US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
EP-4713320-A2 BCAT2 INHIBITORS Agios Pharmaceuticals, Inc. (US) 2026-03-25 EP disclosed
EP-4706683-A2 CHEWABLE FORMULATIONS Elanco Tiergesundheit AG (CH) 2026-03-11 EP disclosed
WO-1996040084-A1 COMPOSITIONS AND METHODS FOR USE OF PRESSURE SENSITIVE ADHESIVE TRANSDERMAL DEVICES CONTAINING A BIOADHESIVE HUMECTANT NOVEN PHARMACEUTICALS, INC. (US) 1996-12-19 WO disclosed
US-5446070-A Flexible, finite, bioadhesive, therapeutical agent in solid form NOVER PHARMACEUTICALS, INC. (US) 1995-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070042969-A1 Combination therapy for pain in painful diabetic neuropathy GRIN2B, GRIN2A, GRIN3A SLC6A19 475/4885ALDH1A1 2350/4885HSD17B3 3117/4885
US-20110263526-A1 Nitric Oxide Releasing Prodrugs of Therapeutic Agents NOS2, NOS1, NOS3 SLC6A19 305/4885ALDH1A1 204/4885HSD17B3 774/4885
US-20070043120-A1 Therapeutic combination for painful medical conditions PDE1B, CA2, CACNA1S SLC6A19 343/4885ALDH1A1 2182/4885HSD17B3 2206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.