Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23653775 | 0.84 | L3MBTL1 (0.51) | PTGER1PTGER4PTGER3PTGER2KDM4E | |
| SCHEMBL1419560 | 0.81 | KMT2A (0.53) | PTGER1PTGER4PTGER3PTGER2KDM4E | |
| SCHEMBL12310073 | 0.80 | LMNA (0.53) | LMNAL3MBTL1MAPTADRB2ADRB1 | |
| SCHEMBL745791 | 0.78 | CYP1A2 (0.49) | LMNAKDM4EADRB2ADRB1CYP1A2 | |
| SCHEMBL13392151 | 0.78 | LMNA (0.47) | LMNAKDM4EADRB2ADRB1CYP1A2 | |
| SCHEMBL13410928 | 0.78 | CYP1A2 (0.49) | LMNAKDM4EADRB2ADRB1CYP1A2 | |
| SCHEMBL12634639 | 0.78 | ELANE (0.52) | PTGER1PTGER4PTGER3PTGER2LMNA | |
| SCHEMBL8520662 | 0.78 | APAF1 (0.59) | PTGER1PTGER4PTGER3PTGER2KDM4E | |
| SCHEMBL750165 | 0.77 | ALOX15 (0.48) | LMNAKDM4EADRB2ADRB1CYP1A2 | |
| SCHEMBL10380337 | 0.76 | HRH1 (0.54) | LMNAL3MBTL1ADRB2ADRB1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101351448-A | Novel 1-benzyl-4-piperidinamines for the treatment of COPD and asthma | ASTRAZENECA AB (SE) | 2009-01-21 | — | — | CN | disclosed |