Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.47 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.47 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | PREP | P48147 | 3/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27757433 | 1.00 | TMEM97 (0.52) | TMEM97SIGMAR1TSHRL3MBTL1KDM4E | |
| SCHEMBL6141635 | 0.89 | FKBP1A (0.51) | TMEM97SIGMAR1TSHRL3MBTL1KDM4E | |
| SCHEMBL15298942 | 0.89 | FKBP1A (0.51) | TMEM97SIGMAR1TSHRL3MBTL1KDM4E | |
| SCHEMBL19120482 | 0.89 | PDK1 (0.52) | TSHRL3MBTL1KDM4ELMNACACNA1A | |
| SCHEMBL13227741 | 0.88 | SIGMAR1 (0.53) | TMEM97SIGMAR1PREPPDK1PDK2 | |
| SCHEMBL7423869 | 0.87 | POLB (0.51) | TSHRL3MBTL1KDM4ELMNACACNA1A | |
| SCHEMBL13227752 | 0.86 | PDK1 (0.49) | TMEM97SIGMAR1FKBP1APREPPDK1 | |
| SCHEMBL27757403 | 0.86 | TMEM97 (0.49) | TMEM97SIGMAR1TSHRL3MBTL1KDM4E | |
| SCHEMBL27736648 | 0.86 | TMEM97 (0.49) | TMEM97SIGMAR1TSHRL3MBTL1KDM4E | |
| SCHEMBL5548236 | 0.84 | CACNA1A (0.41) | TSHRLMNACACNA1ACACNA2D1CACNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101365693-A | Selected CGRP antagonists, method for the production thereof and use thereof as medicaments | BOEHRINGER INGELHEIM INT (DE) | 2009-02-11 | — | — | CN | disclosed |