Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27736728 | 0.79 | PTGER1 (0.46) | HTR7ALDH1A1MAPTPTGER1SCN9A | |
| SCHEMBL17170720 | 0.76 | TSHR (0.67) | HTR7ALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL13430729 | 0.75 | PTGER1 (0.50) | HTR7ALDH1A1MAPTPTGER1SCN9A | |
| SCHEMBL9429028 | 0.74 | HTR7 (0.47) | HTR7ALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL9343076 | 0.74 | XIAP (0.44) | HTR7ALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL2659054 | 0.74 | GABRA1 (0.47) | ALDH1A1SMN1; SMN2MAPTTSHRALOX5AP | |
| SCHEMBL13430734 | 0.73 | PTGER1 (0.55) | HTR7PTGER1SCN9AKMT2A | |
| SCHEMBL17176324 | 0.71 | ALDH1A1 (0.63) | HTR7ALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL4697569 | 0.70 | ALDH1A1 (0.52) | HTR7ALDH1A1SMN1; SMN2MAPTIMPDH2 | |
| SCHEMBL5018864 | 0.70 | GPR84 (0.67) | ALDH1A1SMN1; SMN2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101268048-A | Carbazole derivatives | SERENEX INC (US) | 2008-09-17 | — | — | CN | disclosed |