Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | RBP4 | P02753 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL615082 | 0.83 | GPR119 (0.48) | GAASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL27737040 | 0.81 | GRM5 (0.48) | GAASMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL16824847 | 0.81 | MAPT (0.42) | GAASMN1; SMN2ALDH1A1LMNARAB9A | |
| SCHEMBL1902630 | 0.80 | NCF1 (0.55) | GAASMN1; SMN2LMNARAB9AMEN1 | |
| SCHEMBL22635909 | 0.80 | NCF1 (0.58) | LMNAKMT2AHTR1ASLC6A2SLC6A4 | |
| SCHEMBL418681 | 0.79 | RBP4 (0.46) | GAASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL3904994 | 0.77 | KMT2A (0.68) | SMN1; SMN2ALDH1A1LMNARAB9AMEN1 | |
| SCHEMBL2456483 | 0.77 | DRD4 (0.58) | ALDH1A1RAB9ADRD2 | |
| SCHEMBL2549123 | 0.76 | GAA (0.67) | GAASMN1; SMN2ALDH1A1RAB9AKMT2A | |
| SCHEMBL2549118 | 0.76 | GAA (0.67) | GAASMN1; SMN2ALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102295636-A | Indol-3-y-carbonyl-piperidin and piperazin-derivatives | — | 2011-12-28 | — | — | CN | disclosed |
| CN-101277945-A | Indol-3-yl-carbonyl-piperidine and piperazine derivatives | HOFFMANN LA ROCHE (CH) | 2008-10-01 | — | — | CN | disclosed |