Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20541090 | 0.82 | AVPR1A (0.39) | ALDH1A1POLBMAPTBRPF1MEN1 | |
| SCHEMBL27679412 | 0.81 | ALDH1A1 (0.41) | ALDH1A1POLBMAPTBRPF1MEN1 | |
| Hydrochloric Acid SCHEMBL27738674 | 0.80 | ALDH1A1 (0.40) | ALDH1A1POLBMAPTBRPF1MEN1 | |
| SCHEMBL4265285 | 0.74 | BRPF1 (0.41) | ALDH1A1POLBMAPTBRPF1MEN1 | |
| Hydrochloric Acid SCHEMBL29450350 | 0.72 | BRPF1 (0.40) | ALDH1A1POLBMAPTBRPF1MEN1 | |
| SCHEMBL9706559 | 0.70 | CYP3A4 (0.33) | ALDH1A1MAPTCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28174282 | 0.69 | BRD4 (0.40) | ALDH1A1MEN1KMT2AHSD17B10HSD17B3 | |
| Hydrochloric Acid SCHEMBL27811171 | 0.67 | AVPR1A (0.41) | ALDH1A1POLBMAPTBRPF1MEN1 | |
| SCHEMBL3421961 | 0.67 | HSD17B3 (0.47) | ALDH1A1BRPF1MEN1KMT2AHSD17B3 | |
| SCHEMBL31345695 | 0.67 | HSD17B3 (0.47) | ALDH1A1BRPF1MEN1KMT2AHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101404987-A | Use of sulfonamide derivatives for the treatment of disorders of the surrogate and nervous systems | SMITHKLINE BEECHAM CORP (US) | 2009-04-08 | — | — | CN | disclosed |