Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | GOT1 | P17174 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.46 |
| ▸ | ACOX1 | Q15067 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29178078 | 0.83 | LMNA (0.44) | LMNAALDH1A1KDM4ETP53CYP3A4 | |
| SCHEMBL17748120 | 0.83 | EGFR (0.54) | LMNAALDH1A1KDM4ETP53CYP3A4 | |
| SCHEMBL28867655 | 0.80 | NPC1 (0.42) | LMNAALDH1A1KDM4ETP53CYP3A4 | |
| SCHEMBL276918 | 0.71 | LMNA (0.52) | LMNAALDH1A1KDM4ETP53CYP3A4 | |
| SCHEMBL329993 | 0.71 | CYP2A6 (0.53) | LMNAALDH1A1KDM4ECYP3A4SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL3440665 | 0.70 | ALDH1A1 (0.43) | LMNAALDH1A1KDM4ETP53CYP3A4 | |
| SCHEMBL30523852 | 0.70 | KDM4E (0.55) | LMNAALDH1A1KDM4ETP53CYP3A4 | |
| SCHEMBL1673296 | 0.70 | KDM4E (0.55) | LMNAALDH1A1KDM4ETP53CYP3A4 | |
| SCHEMBL17295055 | 0.69 | NPC1 (0.53) | LMNAALDH1A1KDM4ETP53CYP3A4 | |
| SCHEMBL3682512 | 0.68 | NPC1 (0.48) | LMNAALDH1A1KDM4ETP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117835980-A | Tetrahydropyrazolopyridine analog ligand of NLRX1 and application thereof | 朗多生物制药股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-115485272-A | PLXDC2 ligands | 朗多生物制药股份有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-101273013-B | Sulfonamide derivative having PGD2 receptor antagonistic activity | SHIONOGI & CO | 2013-06-12 | — | — | CN | disclosed |
| CN-101273013-A | Sulfonamide derivative having PGD2 receptor antagonistic activity | SHIONOGI & CO (JP) | 2008-09-24 | — | — | CN | disclosed |