Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 12/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | OGT | O15294 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97140 | 0.81 | PSMB8 (1.00) | PSMB8KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL30834681 | 0.81 | PSMB8 (1.00) | PSMB8KDM4EALDH1A1GAAMEN1 | |
| Benzo[D]Isoxazole SCHEMBL29366929 | 0.77 | — | — | |
| Benzo[D]Isoxazole SCHEMBL8438 | 0.77 | — | — | |
| Benzo[D]Isoxazole SCHEMBL1355530 | 0.77 | — | — | |
| Benzo[D]Isoxazole SCHEMBL1982876 | 0.75 | TDO2 (0.34) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| Benzo[D]Isoxazole SCHEMBL29184280 | 0.75 | TDO2 (0.34) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| Benzo[D]Isoxazole SCHEMBL28482344 | 0.75 | TDO2 (0.39) | KDM4EALDH1A1GAAMEN1KMT2A | |
| Benzo[D]Isoxazole SCHEMBL5158032 | 0.75 | TDO2 (0.34) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| Benzo[D]Isoxazole SCHEMBL21596877 | 0.75 | TDO2 (0.34) | KDM4EALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101273013-A | Sulfonamide derivative having PGD2 receptor antagonistic activity | SHIONOGI & CO (JP) | 2008-09-24 | — | — | CN | disclosed |