SCHEMBL27740973

SCHEMBL27740973

C=CC=C(C)C(=O)Oc1ccc(N)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.40
TDP1 Q9NUW8 4/20 0.37
THRB P10828 3/20 0.37
MAPT P10636 3/20 0.37
KDM4E B2RXH2 2/20 0.37
GLA P06280 1/20 0.37
GAA P10253 1/20 0.37
BLM P54132 1/20 0.37
CASP6 P55212 1/20 0.37
GFER P55789 1/20 0.37
ELANE P08246 1/20 0.37
PARP10 Q53GL7 1/20 0.36
KMT2A Q03164 4/20 0.36
PRSS1 P07477 3/20 0.36
PRSS2 P07478 3/20 0.36
PRSS3 P35030 3/20 0.36
F2 P00734 2/20 0.36
PKM P14618 2/20 0.36
NR1H4 Q96RI1 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28124338 0.81 ELANE (0.45) TDP1THRBMAPTKDM4EGAA
SCHEMBL29135149 0.78 CYP19A1 (0.47) CYP19A1TDP1THRBMAPTKDM4E
SCHEMBL1263025 0.77 ELANE (0.59) CYP19A1TDP1THRBMAPTKDM4E
SCHEMBL27781517 0.77 TDP1 (0.40) CYP19A1TDP1THRBMAPTKDM4E
SCHEMBL598462 0.76 TDP1 (0.44) CYP19A1TDP1THRBMAPTKDM4E
SCHEMBL4100461 0.75 TDP1 (0.50) CYP19A1TDP1THRBMAPTKDM4E
SCHEMBL18504962 0.75 CYP19A1 (0.36) CYP19A1TDP1THRBMAPTKDM4E
SCHEMBL3291664 0.72 THRB (0.55) CYP19A1TDP1THRBMAPTKDM4E
Ethylene SCHEMBL4257350 0.72 LMNA (0.59) CYP19A1TDP1THRBMAPTKDM4E
SCHEMBL16680922 0.72 ELANE (0.40) CYP19A1TDP1THRBMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101296952-B Anti-reflective coatings AZ ELECTRONIC MATERIALS USA 2014-03-26 CN disclosed
CN-101296952-A Anti-reflective coatings AZ ELECTRONIC MATERIALS USA (US) 2008-10-29 CN disclosed