Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4100461 | 0.86 | TDP1 (0.50) | TDP1MAPTMAPK1KDM4EGLA | |
| SCHEMBL1263025 | 0.83 | ELANE (0.59) | TDP1MAPTMAPK1KDM4EGLA | |
| SCHEMBL222240 | 0.82 | LMNA (0.64) | TDP1MAPTMAPK1KDM4EGLA | |
| SCHEMBL1044505 | 0.80 | LMNA (0.61) | TDP1MAPTMAPK1KDM4EGLA | |
| SCHEMBL11456568 | 0.80 | LMNA (0.61) | TDP1MAPTMAPK1KDM4EGLA | |
| SCHEMBL6618980 | 0.80 | CES2 (0.52) | MAPTGAAPARP10LMNAALDH1A1 | |
| SCHEMBL4447324 | 0.80 | LMNA (0.68) | GAALMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL24158 | 0.80 | ELANE (0.48) | TDP1MAPTKDM4EGLAGAA | |
| SCHEMBL27933475 | 0.80 | PARP10 (0.50) | TDP1MAPTMAPK1KDM4EGLA | |
| Hydrochloric Acid SCHEMBL28309210 | 0.80 | LMNA (0.61) | TDP1MAPTMAPK1KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230392173-A1 | ENGINEERED BIOSYNTHETIC PATHWAY FOR PRODUCTION OF 4-AMINOPHENYLETHYLAMINE BY FERMENTATION | ZYMERGEN INC. (US) | 2023-12-07 | — | — | US | claimed |
| CN-116368233-A | Engineered biosynthetic pathway for the production of 4-aminophenylamine by fermentation | 齐默尔根公司 | 2023-06-30 | — | — | CN | claimed |
| EP-4200430-A1 | ENGINEERED BIOSYNTHETIC PATHWAY FOR PRODUCTION OF 4-AMINOPHENYLETHYLAMINE BY FERMENTATION | Zymergen Inc. (US) | 2023-06-28 | — | — | EP | claimed |
| WO-2022040457-A1 | ENGINEERED BIOSYNTHETIC PATHWAY FOR PRODUCTION OF 4-AMINOPHENYLETHYLAMINE BY FERMENTATION | ZYMERGEN INC. (US) | 2022-02-24 | — | — | WO | claimed |
| CN-106471120-B | Method for producing aniline derivatives from carbon sources by fermentation | 国立研究开发法人科学技术振兴机构 | 2020-07-03 | — | — | CN | claimed |
| US-10655153-B2 | Chemoenzymatic synthesis of peptide beta-lactones and beta-hydroxy acids | WASHINGTON UNIVERSITY (US) | 2020-05-19 | — | — | US | claimed |
| US-20180265905-A1 | CHEMOENZYMATIC SYNTHESIS OF PEPTIDE BETA-LACTONES AND BETA-HYDROXY ACIDS | WASHINGTON UNIVERSITY (US) | 2018-09-20 | — | — | US | claimed |
| US-9920343-B2 | Method for producing aniline derivative by fermentation from carbon source | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2018-03-20 | — | — | US | claimed |
| US-20170022528-A1 | METHOD FOR PRODUCING ANILINE DERIVATIVE BY FERMENTATION FROM CARBON SOURCE | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2017-01-26 | — | — | US | claimed |
| EP-3121275-A1 | METHOD FOR PRODUCING ANILINE DERIVATIVE BY FERMENTATION FROM CARBON SOURCE | Japan Science and Technology Agency (JP) | 2017-01-25 | — | — | EP | claimed |
| EP-1380649-B1 | TRANSFORMANT PRODUCING PF1022 SUBSTANCE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND NOVEL BIOSYNTHESIS GENE | MEIJI SEIKA KAISHA (JP) | 2009-10-21 | — | — | EP | claimed |
| US-7432102-B2 | Transformants producing substance pf1022 derivatives, methods for producing the same, and novel biosynthesis genes | MEIJI SEIKA KAISHA, LTD. (JP) | 2008-10-07 | — | — | US | claimed |
| EP-1291417-B1 | NOVEL (R)-2-HYDROXY-3-PHENYLPROPIONATE (D-PHENYLLACTATE) DEHYDROGENASE AND GENE ENCODING THE SAME | MEIJI SEIKA KAISHA (JP) | 2007-02-21 | — | — | EP | claimed |
| CN-1254536-C | Novel(R)-2-hydroxy-3-phenylpropionate (D-phenyllactate) dehydrogenase and gene encoding the same | MEIJI SEIKA KAISHA (JP) | 2006-05-03 | — | — | CN | claimed |
| EP-1490483-A2 | IN VIVO INCORPORATION OF UNNATURAL AMINO ACIDS | The Scripps Research Institute (US) | 2004-12-29 | — | — | EP | claimed |
| US-20040214274-A1 | Transformants producing substance pf1022 derivatives, methods for producing the same, and novel biosynthesis genes | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-10-28 | — | — | US | claimed |
| EP-1380649-A1 | TRANSFORMANT PRODUCING PF1022 SUBSTANCE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND NOVEL BIOSYNTHESIS GENE | MEIJI SEIKA KAISHA LTD. (JP) | 2004-01-14 | — | — | EP | claimed |
| US-20030082575-A1 | Translation system for use in the generation of protein containing adjusted amino acid sequences | THE SCRIPPS RESEARCH INSTITUTE (US) | 2003-05-01 | — | — | US | claimed |
| WO-2002085923-A2 | IN VIVO INCORPORATION OF UNNATURAL AMINO ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2002-10-31 | — | — | WO | claimed |
| EP-1223215-A1 | TRANSFORMANT PRODUCING SECONDARY METABOLITE MODIFIED WITH FUNCTIONAL GROUP AND NOVEL BIOSYNTHESIS GENES | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-17 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214274-A1 | Transformants producing substance pf1022 derivatives, methods for producing the same, and novel biosynthesis genes | GFPT1, FDPS, PSAT1 | TDP1 2690/4885MAPT 3877/4885MAPK1 2857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.