Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NMT1 | P30419 | 2/20 | 0.42 |
| ▸ | NMT2 | O60551 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20607847 | 0.83 | MEN1 (0.47) | MEN1KMT2AHSP90AA1LMNAHPGD | |
| SCHEMBL30892443 | 0.82 | LMNA (0.46) | MEN1KMT2ALMNAHPGDTSHR | |
| SCHEMBL24983853 | 0.82 | LMNA (0.46) | MEN1KMT2ALMNAHPGDTSHR | |
| SCHEMBL27720163 | 0.81 | CTSV (0.51) | MEN1KMT2ALMNAHPGDBRD4 | |
| SCHEMBL27213679 | 0.81 | MAOB (0.48) | MEN1KMT2AHSP90AA1HPGDMAOB | |
| SCHEMBL25367668 | 0.80 | ALDH1A1 (0.51) | KMT2ALMNAHPGDTSHRALDH1A1 | |
| SCHEMBL9321664 | 0.80 | MEN1 (0.52) | MEN1KMT2AHSP90AA1LMNAHPGD | |
| SCHEMBL23796493 | 0.78 | MEN1 (0.59) | MEN1KMT2AHSP90AA1LMNAHPGD | |
| SCHEMBL24983872 | 0.78 | MEN1 (0.48) | MEN1KMT2ALMNAHPGDTSHR | |
| SCHEMBL14882664 | 0.78 | CTSV (0.52) | MEN1KMT2ALMNAHPGDBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101309912-B | Oxazole compound and pharmaceutical composition | OTSUKA PHARMA CO LTD | 2013-09-25 | — | — | CN | disclosed |
| CN-101309912-A | Oxazole compound and pharmaceutical composition | OTSUKA PHARMA CO LTD (JP) | 2008-11-19 | — | — | CN | disclosed |