Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MGMT | P16455 | 2/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035249 | 0.86 | CCNB2 (0.47) | MEN1NPC1RAB9AKMT2AMAOA | |
| SCHEMBL6142808 | 0.78 | KMT2A (0.46) | KMT2ASMN1; SMN2ALDH1A1LMNATRIM24 | |
| SCHEMBL5628914 | 0.78 | ALDH1A1 (0.61) | MEN1NPC1RAB9AKMT2AMAOA | |
| SCHEMBL16616727 | 0.76 | PARP1 (0.49) | MEN1NPC1RAB9AKMT2AMAOA | |
| SCHEMBL27721079 | 0.76 | MAOB (0.44) | MEN1NPC1RAB9AKMT2AMAOA | |
| SCHEMBL510144 | 0.76 | MAOA (0.44) | MEN1NPC1RAB9AKMT2AMAOA | |
| SCHEMBL24631619 | 0.75 | CCNB2 (0.51) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL30134833 | 0.75 | CCNB2 (0.51) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL16305577 | 0.74 | TRIM24 (0.46) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL871969 | 0.74 | ALDH1A1 (0.51) | NPC1SMN1; SMN2ALDH1A1LMNATRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101668767-A | Pyridine derivatives substituted with heterocyclic ring and phosphonoamino group and antifungal agent containing the same | EISAI R&D MAN CO LTD | 2010-03-10 | — | — | CN | disclosed |
| CN-101300250-A | Heterocyclic substituted pyridine derivative and antifungal agent containing the same | EISAI R&D MAN CO LTD (JP) | 2008-11-05 | — | — | CN | disclosed |