Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | DDX3X | O00571 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27767837 | 0.82 | ALDH1A1 (0.58) | ALDH1A1LMNAALOX5CNR1CNR2 | |
| SCHEMBL27742971 | 0.81 | ALOX5 (0.43) | ALDH1A1LMNAALOX5DDX3XF2 | |
| SCHEMBL27742967 | 0.79 | ALDH1A1 (0.45) | ALDH1A1LMNAALOX5F2F10 | |
| SCHEMBL27767901 | 0.77 | LMNA (0.46) | ALDH1A1LMNAALOX5DDX3XCNR1 | |
| SCHEMBL27944346 | 0.72 | ALDH1A1 (0.51) | ALDH1A1LMNAALOX5CNR1CNR2 | |
| SCHEMBL28210277 | 0.70 | ALDH1A1 (0.50) | ALDH1A1LMNACA1CA2CA9 | |
| SCHEMBL18277670 | 0.68 | RPA1 (0.46) | ALDH1A1LMNAALOX5F2F10 | |
| SCHEMBL15995545 | 0.68 | ALDH1A1 (0.56) | ALDH1A1LMNAALOX5CNR1CNR2 | |
| SCHEMBL27889993 | 0.67 | HTT (0.51) | ALDH1A1LMNAALOX5DDX3XF2 | |
| SCHEMBL10180233 | 0.66 | TRPV1 (0.43) | LMNARXFP1CA2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101316841-A | Arylmethylene urea derivative and use thereof | TORAY INDUSTRIES (JP) | 2008-12-03 | — | — | CN | disclosed |