Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 5/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27973045 | 0.80 | TYR (0.42) | ESR1ESR2ALOX15 | |
| SCHEMBL27805061 | 0.77 | ALOX5 (0.45) | ESR1ALOX15SHBG | |
| SCHEMBL11778281 | 0.77 | NOS3 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL28093181 | 0.76 | ALOX15 (0.38) | GABRA1GABRB2MCL1ESR1ESR2 | |
| SCHEMBL15063864 | 0.76 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL27876427 | 0.75 | ALOX15 (0.34) | GABRA1GABRB2ALOX15ALOX12 | |
| SCHEMBL3598860 | 0.74 | — | — | |
| SCHEMBL23671893 | 0.74 | AR (0.32) | GABRA1GABRB2AR | |
| SCHEMBL929876 | 0.72 | — | — | |
| SCHEMBL11494347 | 0.71 | CYP3A4 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10428216-B2 | Golf ball incorporating a mixture of a thermoset and/or thermoplastic composition and a plurality of conductive nanoshelled structures | ACUSHNET COMPANY (US) | 2019-10-01 | — | — | US | disclosed |
| US-20190192922-A1 | GOLF BALL COMPRISING MEDIUM HARDNESS GRADIENT CORE | ACUSHNET COMPANY (US) | 2019-06-27 | — | — | US | disclosed |
| US-10252115-B2 | Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer | ACUSHNET COMPANY (US) | 2019-04-09 | — | — | US | disclosed |
| US-10220263-B2 | Golf balls comprising medium hardness gradient core | ACUSHNET COMPANY (US) | 2019-03-05 | — | — | US | disclosed |
| US-10130848-B2 | Golf ball multilayer core having a gradient quotient | ACUSHNET COMPANY (US) | 2018-11-20 | — | — | US | disclosed |
| US-20180318654-A1 | GOLF BALL INCORPORATING POSITIVE HARDNESS GRADIENT THERMOSET POLYURETHANE OUTER COVER LAYER | ACUSHNET COMPANY (US) | 2018-11-08 | — | — | US | disclosed |
| US-10112081-B2 | Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer | ACUSHNET COMPANY (US) | 2018-10-30 | — | — | US | disclosed |
| US-10035046-B2 | Multilayer core golf ball having hardness gradient within and between each core layer | ACUSHNET COMPANY (US) | 2018-07-31 | — | — | US | disclosed |
| US-10029150-B2 | Golf ball having medium positive gradient quotient and low trans content | ACUSHNET COMPANY (US) | 2018-07-24 | — | — | US | disclosed |
| US-10029151-B2 | Multi-layer cover golf ball having a high acid casing layer | ACUSHNET COMPANY (US) | 2018-07-24 | — | — | US | disclosed |
| US-20090020911-A1 | Method of Treating Rubber Composition with Cure Inihibitor to Create Soft Skin in Golf Ball Core | ACUSHNET COMPANY | 2009-01-22 | — | — | US | disclosed |
| US-20090023865-A1 | Method of Treating Rubber Composition with Cure Inhibitor to Create Soft Skin in Golf Ball Core | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2009-01-22 | — | — | US | disclosed |
| US-20090011863-A1 | Negative Hardness Gradient Inner Core for Dual Core Golf Ball | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2009-01-08 | — | — | US | disclosed |
| US-20090008832-A1 | Negative Hardness Gradient Core Produced from a Low, Temperature-Based Cure Cycle Index | ACUSHNET COMPANY | 2009-01-08 | — | — | US | disclosed |
| US-20090011866-A1 | Multi-Layer Core Golf Ball Having Opposing Hardness Gradient with Steep Gradient Inner Core Layer | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2009-01-08 | — | — | US | disclosed |
| US-20090011859-A1 | Negative Hardness Gradient Inner Core for Dual Core Golf Ball | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2009-01-08 | — | — | US | disclosed |
| US-20080153629-A1 | Thick Outer Cover Layer Golf Ball | ACUSHNET COMPANY | 2008-06-26 | — | — | US | disclosed |
| US-20080146380-A1 | Thick Outer Cover Layer Golf Ball | ACUSHNET COMPANY | 2008-06-19 | — | — | US | disclosed |
| US-20080146378-A1 | Thick Inner Cover Multi-layer Golf Ball | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2008-06-19 | — | — | US | disclosed |
| US-3984940-A | Degradable plastic | REICH MURRAY | 1976-10-12 | — | — | US | disclosed |