Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28932575 | 0.83 | HMGCR (0.46) | ALOX15KDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL2776799 | 0.80 | ALOX15 (0.36) | ALOX15ALOX12KDM4EMAPTMEN1 | |
| SCHEMBL4656377 | 0.79 | TYR (0.52) | ALOX15KDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL28093183 | 0.77 | MEN1 (0.37) | ALOX15KDM4EMAPTMEN1THRB | |
| SCHEMBL27876427 | 0.77 | ALOX15 (0.34) | ALOX15ALOX12GABRA1GABRB2BACE1 | |
| SCHEMBL8848639 | 0.77 | ALOX5 (0.54) | ALOX15KDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL2774334 | 0.76 | GABRA1 (0.33) | ALOX15ALOX12MCL1ESR1ESR2 | |
| SCHEMBL6268956 | 0.74 | HTT (0.49) | MEN1ALDH1A1KMT2AHTT | |
| SCHEMBL1760478 | 0.72 | ALOX15 (0.54) | ALOX15ALOX12KDM4EMAPTMEN1 | |
| SCHEMBL23671893 | 0.71 | AR (0.32) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980372-A | Functionalized benzopyran compounds and uses thereof | 诺沃根有限公司 | 2016-09-28 | — | — | CN | disclosed |