Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782061 | 0.74 | — | — | |
| SCHEMBL1242465 | 0.72 | — | — | |
| SCHEMBL5684007 | 0.72 | MME (0.36) | CHRNB2CHRNA4ALDH1A1CHRNA7 | |
| SCHEMBL12491829 | 0.68 | CHRNB2 (0.35) | CHRNB2CHRNA4ALDH1A1CHRNA7 | |
| SCHEMBL1463307 | 0.68 | CHRNB2 (0.36) | CHRNB2CHRNA4ALDH1A1CHRNA7 | |
| SCHEMBL20134604 | 0.67 | SLC6A3 (0.33) | — | |
| SCHEMBL27676431 | 0.67 | CHRNB2 (0.34) | CHRNB2CHRNA4ALDH1A1CHRNA7 | |
| SCHEMBL624421 | 0.67 | CHRNB2 (0.35) | CHRNB2CHRNA4ALDH1A1CHRNA7NPC1 | |
| SCHEMBL5964811 | 0.67 | ALDH1A1 (0.35) | CHRNB2CHRNA4ALDH1A1CHRNA7 | |
| Bromide SCHEMBL8075410 | 0.65 | CHRNB2 (0.34) | CHRNB2CHRNA4ALDH1A1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101455697-B | Medicine for treating cough and preparation method and use thereof | CHAORONG CHAI | 2012-06-06 | — | — | CN | disclosed |
| CN-101455697-A | Medicine for treating cough and preparation method and use thereof | CHAORONG CHAI (CN) | 2009-06-17 | — | — | CN | disclosed |