Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 6/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27744491 | 0.80 | DHFR (0.55) | MPOTLR8TLR7DHFRNOS1 | |
| SCHEMBL27744565 | 0.78 | MPO (0.53) | MPOTLR8TLR7DHFRNOS1 | |
| SCHEMBL27660234 | 0.77 | MPO (0.61) | MPOTLR8TLR7DHFRNOS1 | |
| SCHEMBL64019 | 0.75 | NOS1 (0.54) | DHFRNOS1 | |
| SCHEMBL30311333 | 0.75 | NOS1 (0.54) | DHFRNOS1 | |
| Bromide SCHEMBL11634826 | 0.74 | DHFR (0.50) | DHFR | |
| Ammonia Solution, Strong SCHEMBL3765509 | 0.74 | NOS1 (0.53) | MPOTLR8TLR7NOS1 | |
| Hydrochloric Acid SCHEMBL29568011 | 0.73 | NOS1 (0.52) | DHFRNOS1 | |
| Hydrochloric Acid SCHEMBL3101407 | 0.73 | NOS1 (0.52) | DHFRNOS1 | |
| Bromide SCHEMBL29695408 | 0.73 | NOS1 (0.52) | DHFRNOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100500215-C | Sustained-release injection containing methotrexate and synergist thereof | JINAN SHUAIHUA MEDICINE SCI TE (CN) | 2009-06-17 | — | — | CN | disclosed |