Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.54 |
| ▸ | DHFR | P00374 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30311333 | 1.00 | NOS1 (0.54) | NOS1DHFRCA1CA2PIK3CG | |
| Hydrochloric Acid SCHEMBL29568011 | 0.98 | NOS1 (0.52) | NOS1DHFRCA1CA2 | |
| Bromide SCHEMBL62895 | 0.98 | NOS1 (0.52) | NOS1DHFRCA1CA2 | |
| Hydrochloric Acid SCHEMBL3101407 | 0.98 | NOS1 (0.52) | NOS1DHFRCA1CA2 | |
| Bromide SCHEMBL29695408 | 0.98 | NOS1 (0.52) | NOS1DHFRCA1CA2 | |
| Bromide SCHEMBL28586331 | 0.97 | NOS1 (0.51) | NOS1DHFRCA1CA2 | |
| SCHEMBL11327528 | 0.86 | PIK3CG (0.50) | NOS1CA1CA2PIK3CG | |
| SCHEMBL31087253 | 0.86 | PIK3CG (0.50) | NOS1CA1CA2PIK3CG | |
| Bromide SCHEMBL11634826 | 0.85 | DHFR (0.50) | DHFR | |
| SCHEMBL14435374 | 0.84 | NOS1 (0.55) | NOS1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118325083-A | Photosensitive polyamic acid ester resin, photosensitive polyamic acid ester resin glue solution, preparation method and application thereof | 深圳先进电子材料国际创新研究院 | 2024-07-12 | — | — | CN | claimed |
| CN-118184655-A | Method for preparing 2, 4-diamino-6-hydroxymethyl pteridine | 四川灵生益制药有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-117801596-A | Photosensitive polyimide resin composition and preparation method and application thereof | 深圳先进电子材料国际创新研究院 | 2024-04-02 | — | — | CN | claimed |
| CN-117447472-A | Synthesis method of 2, 4-diamino-6-chloromethyl pteridine | 南京远淑医药科技有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-102952137-A | Preparation method of 2,4-diamino-6-bromomethyl pteridine | TIANJIN SCIPHARMACN LTD | 2013-03-06 | — | — | CN | claimed |
| US-7081273-B2 | Preparing coating solutions, coating on substrarte; applying vacuum; coagulating; removing solvent and additives from membrane in a series of leaching baths stirred with submersible ultrasonic cleaner;controlling and monitoring coating thickness ; collecting membrane; curing | ACCORD PARTNER LIMITED (VG) | 2006-07-25 | — | — | US | claimed |
| US-20060000766-A1 | Method for producing defect free composite membranes | ACCORD PARTNER LIMITED (VG) | 2006-01-05 | — | — | US | claimed |
| WO-2004011005-A2 | ANTIMICROBIAL 2, 4-DIAMINO-PTERIDINE DERIVATIVES | THE UNIVERSITY OF LIVERPOOL (GB) | 2004-02-05 | — | — | WO | claimed |
| CN-1390234-A | Amine-containing graft polymers, a method for making same, and their use | EXXON CHEMICAL PATENTS INC (US) | 2003-01-08 | — | — | CN | claimed |
| EP-0048002-A2 | Method for preparing N-(4-(((2,4-diamino-6-pteridinyl)-methyl)methylamino)benzoyl)glutamic acid | Farmos Group Ltd. (FI) | 1982-03-24 | — | — | EP | claimed |
| US-4306064-A | Synthesis of 2,4-diamino-6-hydroxymethylpteridine | MONSANTO RESEARCH CORPORATION | 1981-12-15 | — | — | US | claimed |
| US-4080325-A | REACTING TETRAAMINOPYRIMIDINE HYDROCHLORIDE WITH DIHYDROXYACETONE, MULTISTAGE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE | 1978-03-21 | — | — | US | claimed |
| US-3989703-A | Process of preparing N[p-{[(2,4-diamino-6-pteridyl)-methyl]N10 -methylamino}-benzoyl]-glutamic acid | INSTITUTUL ONCOLOGIC (RU) | 1976-11-02 | — | — | US | claimed |
| US-12421187-B2 | Dihydrofolate synthase (DHFS) inhibiting agents and methods of making and using same | WASHINGTON UNIVERISTY (US) | 2025-09-23 | — | — | US | disclosed |
| EP-4549472-A2 | COMPOSITIONS FOR SUNSCREEN COMPOUNDS AND METHODS THEREOF | PMIDG, LLC (US) | 2025-05-07 | — | — | EP | disclosed |
| US-20250114466-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | BYONDIS B.V. (NL) | 2025-04-10 | — | — | US | disclosed |
| US-4079056-A | REACTING 2,4-DIAMINO-6-PTERIDINE-METHANOL-HBR WITH TRIPHENYLPHOSPHINE DIBROMIDE OR PHOSPHORUS TRIBROMIDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1978-03-14 | — | — | US | disclosed |
| US-4077957-A | INTERMEDIATE FOR METHOTREXATE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1978-03-07 | — | — | US | disclosed |
| US-3989703-A | Process of preparing N[p-{[(2,4-diamino-6-pteridyl)-methyl]N10 -methylamino}-benzoyl]-glutamic acid | INSTITUTUL ONCOLOGIC (RU) | 1976-11-02 | — | — | US | disclosed |
| US-3989703-A | Process of preparing N[p-{[(2,4-diamino-6-pteridyl)-methyl]N10 -methylamino}-benzoyl]-glutamic acid | INSTITUTUL ONCOLOGIC (RU) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250114466-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | DHFR, FOLR1, MTHFD2 | NOS1 4167/4885DHFR 1/4885CA1 2964/4885 |
| US-12421187-B2 | Dihydrofolate synthase (DHFS) inhibiting agents and methods of making and using same | DHFR, DHPS, MTHFD1 | NOS1 2595/4885DHFR 1/4885CA1 2717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.