SCHEMBL27744784

SCHEMBL27744784

C=Cc1ccccc1OC(CC)COC(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR2E1 Q9Y466 1/20 0.37
ADRA2C P18825 8/20 0.34
ADRA2B P18089 7/20 0.34
ADRA2A P08913 6/20 0.34
MCHR1 Q99705 1/20 0.33
HTR1A P08908 4/20 0.32
ADRB2 P07550 3/20 0.32
ADRB1 P08588 3/20 0.32
KCNH2 Q12809 2/20 0.32
LMNA P02545 2/20 0.32
SLC6A4 P31645 2/20 0.32
ADRA1A P35348 2/20 0.32
SLC22A1 O15245 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
HTR2A P28223 1/20 0.32
HPGD P15428 2/20 0.31
MEN1 O00255 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27602427 0.83 NR2E1 (0.39) NR2E1ADRA2CMCHR1HTR1AADRB2
SCHEMBL27744776 0.82 ADRA2B (0.33) ADRA2CADRA2BADRA2AHTR1AADRB2
SCHEMBL5373674 0.80 ADRA2A (0.34) ADRA2CADRA2BADRA2ALMNAHPGD
SCHEMBL6279906 0.80 MCHR1 (0.35) ADRA2CADRA2BADRA2AMCHR1HTR1A
SCHEMBL27528404 0.78 MCHR1 (0.42) ADRA2CADRA2BADRA2AMCHR1HTR1A
SCHEMBL29266697 0.78 ALDH1A1 (0.32) ADRA2CADRA2BADRA2ALMNAHPGD
SCHEMBL419697 0.77 ALDH1A1 (0.43) ADRA2CADRA2BADRA2AMCHR1LMNA
SCHEMBL1395548 0.76 LMNA (0.37) ADRA2CADRA2BADRA2AHTR1AADRB2
SCHEMBL29266695 0.75 ALDH1A1 (0.31) ADRA2CADRA2BADRA2ALMNAHPGD
SCHEMBL4543863 0.74 ALDH1A1 (0.33) ADRA2CADRA2BADRA2AHTR1AADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105541659-A Halogenated oxime derivatives and their use as potential acid CIBA SPECIALTY CHEMICALS HOLDING INC 2016-05-04 CN disclosed
CN-102781911-B Latent acids and their use BASF SE 2015-07-22 CN disclosed
CN-102781911-A Latent acids and their use BASF SE 2012-11-14 CN disclosed
CN-100475798-C Sulfonate derivatives and the use therof as latent acids CIBA SC HOLDING AG (CH) 2009-04-08 CN disclosed