Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15969360 | 0.81 | ELANE (0.49) | SMN1; SMN2ALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL15969657 | 0.78 | CES2 (0.49) | LMNARAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL22125723 | 0.77 | ALDH1A1 (0.44) | SMN1; SMN2RAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL24961282 | 0.77 | POLB (0.49) | SMN1; SMN2ALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL10903705 | 0.76 | L3MBTL1 (0.59) | SMN1; SMN2NPC1TP53ALDH1A1KMT2A | |
| SCHEMBL11963886 | 0.75 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL11321880 | 0.75 | AAK1 (0.46) | SMN1; SMN2ALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL213829 | 0.74 | ALDH1A1 (0.51) | LMNASMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL38664774 | 0.74 | ALDH1A1 (0.46) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL27576040 | 0.74 | TDP1 (0.50) | LMNANPC1TP53RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102946882-A | Phenylalanine derivatives and their use as non-peptide glp-1 receptor modulators | ARGUSINA INC | 2013-02-27 | — | — | CN | disclosed |
| CN-101267813-A | Substituted propanamide derivative and pharmaceutical composition containing the same | DAIICHI SANKYO CO LTD (JP) | 2008-09-17 | — | — | CN | disclosed |